Correlation between the rate of morphological changes and rupture of intracranial aneurysms during one cardiac cycle analyzed by 4D-CTA
ObjectiveThis study aimed to analyze the relationship between the rate of morphological changes and intracranial aneurysm rupture during the cardiac cycle.MethodsEighty-four patients with intracranial aneurysms were retrospectively analyzed and divided into the rupture (42 cases) and unruptured (42...
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| Format: | Article |
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Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1235312/full |
| _version_ | 1797668194202157056 |
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| author | Binghao Wang Binghao Wang Binghao Wang Chengen Shen Chengen Shen Zhongzhou Su Zhongzhou Su Xiaohu Nie Xiaohu Nie Jingjing Zhao Jingjing Zhao Sheng Qiu Sheng Qiu Yuntao Li Yuntao Li |
| author_facet | Binghao Wang Binghao Wang Binghao Wang Chengen Shen Chengen Shen Zhongzhou Su Zhongzhou Su Xiaohu Nie Xiaohu Nie Jingjing Zhao Jingjing Zhao Sheng Qiu Sheng Qiu Yuntao Li Yuntao Li |
| author_sort | Binghao Wang |
| collection | DOAJ |
| description | ObjectiveThis study aimed to analyze the relationship between the rate of morphological changes and intracranial aneurysm rupture during the cardiac cycle.MethodsEighty-four patients with intracranial aneurysms were retrospectively analyzed and divided into the rupture (42 cases) and unruptured (42 cases) groups. Four-dimensional computed tomography angiography (4D-CTA) was performed to collect quantitative parameters of aneurysm morphology and calculate the morphological change rate. The potential factors associated with aneurysm rupture were determined by comparing the general clinical data and rate of change in the location and morphology of the aneurysm between the two groups.ResultsEach morphological change rate in the rupture group was generally higher than that of the unruptured group. The rate of dome height change and aneurysm volume change were independent factors associated with aneurysm rupture. ROC curve analysis revealed that the diagnostic accuracy of the aneurysm volume change rate was higher. When the volume change rate was 12.33%, the sensitivity and specificity of rupture were 90.5 and 55.8%, respectively.ConclusionThe rate of change in dome height and volume of intracranial aneurysms during one cardiac cycle were independent factors associated with aneurysm rupture. |
| first_indexed | 2024-03-11T20:25:03Z |
| format | Article |
| id | doaj.art-2e4fa78f5cd843a383d39d334c685fd8 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-03-11T20:25:03Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-2e4fa78f5cd843a383d39d334c685fd82023-10-02T15:20:53ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-10-011410.3389/fneur.2023.12353121235312Correlation between the rate of morphological changes and rupture of intracranial aneurysms during one cardiac cycle analyzed by 4D-CTABinghao Wang0Binghao Wang1Binghao Wang2Chengen Shen3Chengen Shen4Zhongzhou Su5Zhongzhou Su6Xiaohu Nie7Xiaohu Nie8Jingjing Zhao9Jingjing Zhao10Sheng Qiu11Sheng Qiu12Yuntao Li13Yuntao Li14Department of Neurosurgery, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, ChinaHuzhou Key Laboratory of Basic Research and Clinical Translation for Neuromodulation, Huzhou, ChinaDepartment of Neurosurgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, ChinaDepartment of Neurosurgery, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, ChinaHuzhou Key Laboratory of Basic Research and Clinical Translation for Neuromodulation, Huzhou, ChinaDepartment of Neurosurgery, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, ChinaHuzhou Key Laboratory of Basic Research and Clinical Translation for Neuromodulation, Huzhou, ChinaDepartment of Neurosurgery, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, ChinaHuzhou Key Laboratory of Basic Research and Clinical Translation for Neuromodulation, Huzhou, ChinaHuzhou Key Laboratory of Basic Research and Clinical Translation for Neuromodulation, Huzhou, ChinaDepartment of Hospital Infection Control, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, ChinaDepartment of Neurosurgery, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, ChinaHuzhou Key Laboratory of Basic Research and Clinical Translation for Neuromodulation, Huzhou, ChinaDepartment of Neurosurgery, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, ChinaHuzhou Key Laboratory of Basic Research and Clinical Translation for Neuromodulation, Huzhou, ChinaObjectiveThis study aimed to analyze the relationship between the rate of morphological changes and intracranial aneurysm rupture during the cardiac cycle.MethodsEighty-four patients with intracranial aneurysms were retrospectively analyzed and divided into the rupture (42 cases) and unruptured (42 cases) groups. Four-dimensional computed tomography angiography (4D-CTA) was performed to collect quantitative parameters of aneurysm morphology and calculate the morphological change rate. The potential factors associated with aneurysm rupture were determined by comparing the general clinical data and rate of change in the location and morphology of the aneurysm between the two groups.ResultsEach morphological change rate in the rupture group was generally higher than that of the unruptured group. The rate of dome height change and aneurysm volume change were independent factors associated with aneurysm rupture. ROC curve analysis revealed that the diagnostic accuracy of the aneurysm volume change rate was higher. When the volume change rate was 12.33%, the sensitivity and specificity of rupture were 90.5 and 55.8%, respectively.ConclusionThe rate of change in dome height and volume of intracranial aneurysms during one cardiac cycle were independent factors associated with aneurysm rupture.https://www.frontiersin.org/articles/10.3389/fneur.2023.1235312/full4D-CTAintracranial aneurysmmorphological change raterupture factorscardiac cycle |
| spellingShingle | Binghao Wang Binghao Wang Binghao Wang Chengen Shen Chengen Shen Zhongzhou Su Zhongzhou Su Xiaohu Nie Xiaohu Nie Jingjing Zhao Jingjing Zhao Sheng Qiu Sheng Qiu Yuntao Li Yuntao Li Correlation between the rate of morphological changes and rupture of intracranial aneurysms during one cardiac cycle analyzed by 4D-CTA Frontiers in Neurology 4D-CTA intracranial aneurysm morphological change rate rupture factors cardiac cycle |
| title | Correlation between the rate of morphological changes and rupture of intracranial aneurysms during one cardiac cycle analyzed by 4D-CTA |
| title_full | Correlation between the rate of morphological changes and rupture of intracranial aneurysms during one cardiac cycle analyzed by 4D-CTA |
| title_fullStr | Correlation between the rate of morphological changes and rupture of intracranial aneurysms during one cardiac cycle analyzed by 4D-CTA |
| title_full_unstemmed | Correlation between the rate of morphological changes and rupture of intracranial aneurysms during one cardiac cycle analyzed by 4D-CTA |
| title_short | Correlation between the rate of morphological changes and rupture of intracranial aneurysms during one cardiac cycle analyzed by 4D-CTA |
| title_sort | correlation between the rate of morphological changes and rupture of intracranial aneurysms during one cardiac cycle analyzed by 4d cta |
| topic | 4D-CTA intracranial aneurysm morphological change rate rupture factors cardiac cycle |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1235312/full |
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