New Hypertension Guidelines from the National Institute for Health and Clinical Excellence and the British Hypertension Society
A joint initiative between the National Institute for Health and Clinical Excellence (NICE) and the British Hypertension Society (BHS) has led to the publication of new guidelines for the management of hypertension in the community. Recent trial evidence highlighting the increased incidence of new-o...
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| Format: | Article |
| Language: | English |
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SAGE Publications
2006-06-01
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| Series: | Journal of the Renin-Angiotensin-Aldosterone System |
| Online Access: | https://doi.org/10.3317/jraas.2006.011 |
| _version_ | 1797281866265395200 |
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| author | Peter Sever |
| author_facet | Peter Sever |
| author_sort | Peter Sever |
| collection | DOAJ |
| description | A joint initiative between the National Institute for Health and Clinical Excellence (NICE) and the British Hypertension Society (BHS) has led to the publication of new guidelines for the management of hypertension in the community. Recent trial evidence highlighting the increased incidence of new-onset diabetes in those exposed to beta-blocker-based treatment regimens, with or without diuretics, compared with those based on calcium channel blockers (CCBs) or angiotensin-converting enzyme (ACE-Is) inhibitors has led to a recommendation that in the uncomplicated patient, beta-blockers are no longer considered suitable options for first-line therapy. Together with mounting A evidence that age and ethnicity dictate blood pressure (BP) responsiveness to different classes of antihypertensive drugs, the ACD algorithm is now proposed (formerly ABCD), with ACE inhibitors (ACE-Is) (or angiotensin receptor blockers [ARBs] when ACE-Is are poorly tolerated) preferred in younger patients and or patients and CCBs or diuretics preferred for older patientsand in black patients of any age. Pathophysiological considerations have influenced proposals for combination therapies with CCBs or diuretics added to older patients. Health economic analyses have ACE-Is in younger patients and vice versa in clearly indicated the cost effectiveness of CCBs which are now elevated to equal standing with diuretics in older patients. |
| first_indexed | 2024-03-07T17:03:37Z |
| format | Article |
| id | doaj.art-2e4fb4f406b449de853c89abb4cf195f |
| institution | Directory Open Access Journal |
| issn | 1470-3203 |
| language | English |
| last_indexed | 2024-03-07T17:03:37Z |
| publishDate | 2006-06-01 |
| publisher | SAGE Publications |
| record_format | Article |
| series | Journal of the Renin-Angiotensin-Aldosterone System |
| spelling | doaj.art-2e4fb4f406b449de853c89abb4cf195f2024-03-03T02:50:46ZengSAGE PublicationsJournal of the Renin-Angiotensin-Aldosterone System1470-32032006-06-01710.3317/jraas.2006.011New Hypertension Guidelines from the National Institute for Health and Clinical Excellence and the British Hypertension SocietyPeter SeverA joint initiative between the National Institute for Health and Clinical Excellence (NICE) and the British Hypertension Society (BHS) has led to the publication of new guidelines for the management of hypertension in the community. Recent trial evidence highlighting the increased incidence of new-onset diabetes in those exposed to beta-blocker-based treatment regimens, with or without diuretics, compared with those based on calcium channel blockers (CCBs) or angiotensin-converting enzyme (ACE-Is) inhibitors has led to a recommendation that in the uncomplicated patient, beta-blockers are no longer considered suitable options for first-line therapy. Together with mounting A evidence that age and ethnicity dictate blood pressure (BP) responsiveness to different classes of antihypertensive drugs, the ACD algorithm is now proposed (formerly ABCD), with ACE inhibitors (ACE-Is) (or angiotensin receptor blockers [ARBs] when ACE-Is are poorly tolerated) preferred in younger patients and or patients and CCBs or diuretics preferred for older patientsand in black patients of any age. Pathophysiological considerations have influenced proposals for combination therapies with CCBs or diuretics added to older patients. Health economic analyses have ACE-Is in younger patients and vice versa in clearly indicated the cost effectiveness of CCBs which are now elevated to equal standing with diuretics in older patients.https://doi.org/10.3317/jraas.2006.011 |
| spellingShingle | Peter Sever New Hypertension Guidelines from the National Institute for Health and Clinical Excellence and the British Hypertension Society Journal of the Renin-Angiotensin-Aldosterone System |
| title | New Hypertension Guidelines from the National Institute for Health and Clinical Excellence and the British Hypertension Society |
| title_full | New Hypertension Guidelines from the National Institute for Health and Clinical Excellence and the British Hypertension Society |
| title_fullStr | New Hypertension Guidelines from the National Institute for Health and Clinical Excellence and the British Hypertension Society |
| title_full_unstemmed | New Hypertension Guidelines from the National Institute for Health and Clinical Excellence and the British Hypertension Society |
| title_short | New Hypertension Guidelines from the National Institute for Health and Clinical Excellence and the British Hypertension Society |
| title_sort | new hypertension guidelines from the national institute for health and clinical excellence and the british hypertension society |
| url | https://doi.org/10.3317/jraas.2006.011 |
| work_keys_str_mv | AT petersever newhypertensionguidelinesfromthenationalinstituteforhealthandclinicalexcellenceandthebritishhypertensionsociety |