Regeneration of damaged osteoporotic bone tissue with synthetic biomaterials

In some cases in oral and maxillofacial surgery, bone regeneration is required in large quantities. One of these cases is osteoporosis. This paper aims to show the new approach to solving this problem of impaired healing of bone defects in the jaw, as well as in other bones, with the use of syntheti...

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Main Authors: Petrović Nenad D., Ajduković Zorica R., Kenić-Marinković Dragana M.
Format: Article
Language:English
Published: Savez inženjera i tehničara Srbije 2014-01-01
Series:Tehnika
Subjects:
Online Access:http://scindeks-clanci.ceon.rs/data/pdf/0040-2176/2014/0040-21761406907P.pdf
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author Petrović Nenad D.
Ajduković Zorica R.
Kenić-Marinković Dragana M.
author_facet Petrović Nenad D.
Ajduković Zorica R.
Kenić-Marinković Dragana M.
author_sort Petrović Nenad D.
collection DOAJ
description In some cases in oral and maxillofacial surgery, bone regeneration is required in large quantities. One of these cases is osteoporosis. This paper aims to show the new approach to solving this problem of impaired healing of bone defects in the jaw, as well as in other bones, with the use of synthetic biomaterials whose properties resemble the natural bone. Latest development in this area present an effort to create local drug-delivery systems for BMPs and growth factors, direct delivery of MSCs, as well as scaffolds for osteoconduction and also to utilize nanotechnology to synthesize composite biomaterials, predominantly based on HAp and polymers, that would mimic the natural bone nanocomposite architecture. There is also a tendency to create injectable biomaterials for simplified application.
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spelling doaj.art-2e51262d94694338afa856f4b56477b52022-12-21T22:26:19ZengSavez inženjera i tehničara SrbijeTehnika0040-21762560-30862014-01-0169690791310.5937/tehnika1406907P0040-21761406907PRegeneration of damaged osteoporotic bone tissue with synthetic biomaterialsPetrović Nenad D.0Ajduković Zorica R.1Kenić-Marinković Dragana M.2Univeristy of Niš, Faculty of Medicine, Niš, SerbiaUniversity of Niš, Faculty of Medicine - Stomatology Clinics, Niš, SerbiaPrivatna stomatološka ordinacija 'Kalodent', NišIn some cases in oral and maxillofacial surgery, bone regeneration is required in large quantities. One of these cases is osteoporosis. This paper aims to show the new approach to solving this problem of impaired healing of bone defects in the jaw, as well as in other bones, with the use of synthetic biomaterials whose properties resemble the natural bone. Latest development in this area present an effort to create local drug-delivery systems for BMPs and growth factors, direct delivery of MSCs, as well as scaffolds for osteoconduction and also to utilize nanotechnology to synthesize composite biomaterials, predominantly based on HAp and polymers, that would mimic the natural bone nanocomposite architecture. There is also a tendency to create injectable biomaterials for simplified application.http://scindeks-clanci.ceon.rs/data/pdf/0040-2176/2014/0040-21761406907P.pdfosteoporosisbio compositedrug deliveryscaffoldbone regenerationtissue engineering
spellingShingle Petrović Nenad D.
Ajduković Zorica R.
Kenić-Marinković Dragana M.
Regeneration of damaged osteoporotic bone tissue with synthetic biomaterials
Tehnika
osteoporosis
bio composite
drug delivery
scaffold
bone regeneration
tissue engineering
title Regeneration of damaged osteoporotic bone tissue with synthetic biomaterials
title_full Regeneration of damaged osteoporotic bone tissue with synthetic biomaterials
title_fullStr Regeneration of damaged osteoporotic bone tissue with synthetic biomaterials
title_full_unstemmed Regeneration of damaged osteoporotic bone tissue with synthetic biomaterials
title_short Regeneration of damaged osteoporotic bone tissue with synthetic biomaterials
title_sort regeneration of damaged osteoporotic bone tissue with synthetic biomaterials
topic osteoporosis
bio composite
drug delivery
scaffold
bone regeneration
tissue engineering
url http://scindeks-clanci.ceon.rs/data/pdf/0040-2176/2014/0040-21761406907P.pdf
work_keys_str_mv AT petrovicnenadd regenerationofdamagedosteoporoticbonetissuewithsyntheticbiomaterials
AT ajdukoviczoricar regenerationofdamagedosteoporoticbonetissuewithsyntheticbiomaterials
AT kenicmarinkovicdraganam regenerationofdamagedosteoporoticbonetissuewithsyntheticbiomaterials