Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowth
Drug-induced gingival overgrowth is a frequently observed adverse effect of antihypertensive drug calcium channel blockers (CCBs). Gingival enlargements are more common with the dihydropyridine class of CCBs. The fourth-generation dihydropyridine CCB Cilnidipine was introduced in 1995 and is used as...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Journal of Indian Society of Periodontology |
| Subjects: | |
| Online Access: | http://www.jisponline.com/article.asp?issn=0972-124X;year=2019;volume=23;issue=4;spage=377;epage=380;aulast=Gopinath |
| _version_ | 1818296407722819584 |
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| author | Sameera Gopinath Vadakkedath Venugopal Harishkumar Vediyera Chandroth Santhosh Sreekanth Puthalath |
| author_facet | Sameera Gopinath Vadakkedath Venugopal Harishkumar Vediyera Chandroth Santhosh Sreekanth Puthalath |
| author_sort | Sameera Gopinath |
| collection | DOAJ |
| description | Drug-induced gingival overgrowth is a frequently observed adverse effect of antihypertensive drug calcium channel blockers (CCBs). Gingival enlargements are more common with the dihydropyridine class of CCBs. The fourth-generation dihydropyridine CCB Cilnidipine was introduced in 1995 and is used as an antihypertensive agent for patients in the Indian subcontinent. This is the first report in literature to document an isolated case of generalized gingival overgrowth induced by the long-term use of low dose of cilnidipine in an elderly female patient who is under antihypertensive therapy. Gingival overgrowth is an adverse drug reaction of new-generation CCB Cilnidipine when administered even as low-dose antihypertensive therapy agent. Physicians and dentists should identify such late changes in susceptible individuals. |
| first_indexed | 2024-12-13T04:03:03Z |
| format | Article |
| id | doaj.art-2e52faf618124c238dd9c7329869162d |
| institution | Directory Open Access Journal |
| issn | 0972-124X |
| language | English |
| last_indexed | 2024-12-13T04:03:03Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Society of Periodontology |
| spelling | doaj.art-2e52faf618124c238dd9c7329869162d2022-12-22T00:00:21ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2019-01-0123437738010.4103/jisp.jisp_557_18Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowthSameera GopinathVadakkedath Venugopal HarishkumarVediyera Chandroth SanthoshSreekanth PuthalathDrug-induced gingival overgrowth is a frequently observed adverse effect of antihypertensive drug calcium channel blockers (CCBs). Gingival enlargements are more common with the dihydropyridine class of CCBs. The fourth-generation dihydropyridine CCB Cilnidipine was introduced in 1995 and is used as an antihypertensive agent for patients in the Indian subcontinent. This is the first report in literature to document an isolated case of generalized gingival overgrowth induced by the long-term use of low dose of cilnidipine in an elderly female patient who is under antihypertensive therapy. Gingival overgrowth is an adverse drug reaction of new-generation CCB Cilnidipine when administered even as low-dose antihypertensive therapy agent. Physicians and dentists should identify such late changes in susceptible individuals.http://www.jisponline.com/article.asp?issn=0972-124X;year=2019;volume=23;issue=4;spage=377;epage=380;aulast=GopinathAdverse drug reactioncalcium channel blockercilnidipinedihydropyridinegingival overgrowth |
| spellingShingle | Sameera Gopinath Vadakkedath Venugopal Harishkumar Vediyera Chandroth Santhosh Sreekanth Puthalath Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowth Journal of Indian Society of Periodontology Adverse drug reaction calcium channel blocker cilnidipine dihydropyridine gingival overgrowth |
| title | Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowth |
| title_full | Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowth |
| title_fullStr | Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowth |
| title_full_unstemmed | Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowth |
| title_short | Case report on low dose of Cilnidipine: A fourth-generation calcium channel blocker-induced gingival overgrowth |
| title_sort | case report on low dose of cilnidipine a fourth generation calcium channel blocker induced gingival overgrowth |
| topic | Adverse drug reaction calcium channel blocker cilnidipine dihydropyridine gingival overgrowth |
| url | http://www.jisponline.com/article.asp?issn=0972-124X;year=2019;volume=23;issue=4;spage=377;epage=380;aulast=Gopinath |
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