Actual questions of treatment of urinary tract infection in neonates

The aim of this study was to evaluate the structure of etiotropic therapy used in the treatment of urinary tract infection in newborns, the frequency of using off-label etiotropic medicines, and assess the incidence of adverse drugs reactions (ADR). The work was carried out by a retrospective pharma...

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Main Authors: S. K. Zyryanov, O. A. Shulakova, K. G. Gurevich
Format: Article
Language:Russian
Published: Izdatelstvo OKI 2018-05-01
Series:Качественная клиническая практика
Subjects:
Online Access:https://www.clinvest.ru/jour/article/view/78
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author S. K. Zyryanov
O. A. Shulakova
K. G. Gurevich
author_facet S. K. Zyryanov
O. A. Shulakova
K. G. Gurevich
author_sort S. K. Zyryanov
collection DOAJ
description The aim of this study was to evaluate the structure of etiotropic therapy used in the treatment of urinary tract infection in newborns, the frequency of using off-label etiotropic medicines, and assess the incidence of adverse drugs reactions (ADR). The work was carried out by a retrospective pharmacoepidemiology analysis of children hospitalized patient history (form 003/y) with infectious diseases in the period of the newborn. The object of the study is a case history of a stationary patient, the main method of research is the collection and analysis of information, the statistical processing of the data obtained. During the analysis, all the selected medical records were divided into two groups: the first - children, with the course of urinary tract infection, the second - with the course of infectious diseases of other localization. During the study it was demonstrated that the use of etiotropic therapy in children with urinary infection is higher than in children with the course of the infectious process of other localization. The frequency of off-label prescriptions for the treatment of urinary tract infection is 51%, and the incidence of ADR in the case of unadapted appointments is 1,4 times higher.
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spelling doaj.art-2e55293ce72f4bdbb1b595ad491cf9942024-03-14T18:09:04ZrusIzdatelstvo OKIКачественная клиническая практика2588-05192618-84732018-05-0101465078Actual questions of treatment of urinary tract infection in neonatesS. K. Zyryanov0O. A. Shulakova1K. G. Gurevich2ФГАОУ ВО «Российский университет дружбы народов», г. МоскваФГАУ ВО «Российский университет дружбы народов», г. МоскваФГБОУ ВО МГМСУ им. А.И. Евдокимова Минздрава России, г. МоскваThe aim of this study was to evaluate the structure of etiotropic therapy used in the treatment of urinary tract infection in newborns, the frequency of using off-label etiotropic medicines, and assess the incidence of adverse drugs reactions (ADR). The work was carried out by a retrospective pharmacoepidemiology analysis of children hospitalized patient history (form 003/y) with infectious diseases in the period of the newborn. The object of the study is a case history of a stationary patient, the main method of research is the collection and analysis of information, the statistical processing of the data obtained. During the analysis, all the selected medical records were divided into two groups: the first - children, with the course of urinary tract infection, the second - with the course of infectious diseases of other localization. During the study it was demonstrated that the use of etiotropic therapy in children with urinary infection is higher than in children with the course of the infectious process of other localization. The frequency of off-label prescriptions for the treatment of urinary tract infection is 51%, and the incidence of ADR in the case of unadapted appointments is 1,4 times higher.https://www.clinvest.ru/jour/article/view/78новорождённыеинфекция мочевыделительной системыэтиотропная терапияoff-labelнежелательные реакциифармакоэпидемиологическое исследованиеnewbornurinary tract infectionetiotropic therapyoff-labeladverse reactionspharmacoepidemiology study
spellingShingle S. K. Zyryanov
O. A. Shulakova
K. G. Gurevich
Actual questions of treatment of urinary tract infection in neonates
Качественная клиническая практика
новорождённые
инфекция мочевыделительной системы
этиотропная терапия
off-label
нежелательные реакции
фармакоэпидемиологическое исследование
newborn
urinary tract infection
etiotropic therapy
off-label
adverse reactions
pharmacoepidemiology study
title Actual questions of treatment of urinary tract infection in neonates
title_full Actual questions of treatment of urinary tract infection in neonates
title_fullStr Actual questions of treatment of urinary tract infection in neonates
title_full_unstemmed Actual questions of treatment of urinary tract infection in neonates
title_short Actual questions of treatment of urinary tract infection in neonates
title_sort actual questions of treatment of urinary tract infection in neonates
topic новорождённые
инфекция мочевыделительной системы
этиотропная терапия
off-label
нежелательные реакции
фармакоэпидемиологическое исследование
newborn
urinary tract infection
etiotropic therapy
off-label
adverse reactions
pharmacoepidemiology study
url https://www.clinvest.ru/jour/article/view/78
work_keys_str_mv AT skzyryanov actualquestionsoftreatmentofurinarytractinfectioninneonates
AT oashulakova actualquestionsoftreatmentofurinarytractinfectioninneonates
AT kggurevich actualquestionsoftreatmentofurinarytractinfectioninneonates