Long noncoding RNA TLNC1 promotes the growth and metastasis of liver cancer via inhibition of p53 signaling

Long noncoding RNA TLNC1 promotes the growth and metastasis of liver cancer via inhibition of p53 signaling

Abstract Background Long non-coding RNAs (lncRNAs) have been demonstrated to play vital roles in cancer development and progression. However, their biological roles and function mechanisms in liver cancer remain largely unknown. Methods RNA-seq was performed with clinical hepatoma tissues and paired...

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Bibliographic Details
Main Authors: Kefei Yuan, Jiang Lan, Lin Xu, Xuping Feng, Haotian Liao, Kunlin Xie, Hong Wu, Yong Zeng
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Molecular Cancer
Subjects:
lncRNA
TLNC1
TPR
p53
Liver cancer
Online Access:https://doi.org/10.1186/s12943-022-01578-w

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