Role of Hepatitis B virus capsid phosphorylation in nucleocapsid disassembly and covalently closed circular DNA formation.

Role of Hepatitis B virus capsid phosphorylation in nucleocapsid disassembly and covalently closed circular DNA formation.

Hepatitis B virus (HBV) delivers a partially double-stranded, relaxed circular (RC) DNA genome in complete virions to the host cell nucleus for conversion to the covalently closed circular (CCC) DNA, which establishes and sustains viral infection. An overlength pregenomic RNA (pgRNA) is then transcr...

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Bibliographic Details
Main Authors:	Jun Luo, Ji Xi, Lu Gao, Jianming Hu
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2020-03-01
Series:	PLoS Pathogens
Online Access:	https://doi.org/10.1371/journal.ppat.1008459

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