The impacts of the National Medication Price-Negotiated Policy on the financial burden of cancer patients in Shandong province, China: an interrupted time series analysis

Abstract Background In order to further regulate the price of anticancer medication and alleviate the financial burden of cancer patients, the Chinese government implemented the National Medication Price-Negotiated Policy (NMPNP) in 2017. This study aims to assess the impacts of implementation of th...

Full description

Bibliographic Details
Main Authors: Yi Ding, Chao Zheng, Xiaolin Wei, Qi Zhang, Qiang Sun
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Public Health
Subjects:
Online Access:https://doi.org/10.1186/s12889-022-14525-7
_version_ 1828265063173062656
author Yi Ding
Chao Zheng
Xiaolin Wei
Qi Zhang
Qiang Sun
author_facet Yi Ding
Chao Zheng
Xiaolin Wei
Qi Zhang
Qiang Sun
author_sort Yi Ding
collection DOAJ
description Abstract Background In order to further regulate the price of anticancer medication and alleviate the financial burden of cancer patients, the Chinese government implemented the National Medication Price-Negotiated Policy (NMPNP) in 2017. This study aims to assess the impacts of implementation of the NMPNP on the access of anticancer medication and the financial burden for cancer patients in Shandong province, and to provide evidence to inform the design of similar policies in other developing countries. Methods A quasi-experiment design of an interrupt time series analysis was conducted. The month of September 2017 was taken as the intervention point when the Shandong Provincial Reimbursement Drug Lists was updated based on the result of the NMPNP in 2017. The data used were the aggregated monthly claim data of cancer patients from 2016 to 2021, which were obtained from four cities in Shandong province. The outpatient and inpatient care visits per capita, proportion of OOP expenditure and medication costs in outpatient and inpatient medical costs were used as outcome variables. A segmented regression model was used to analyze the change of the access of anticancer medication and the financial burden for cancer patients. Results The outpatient care visits per capita significantly decreased after the intervention. Compared to preintervention trend, the proportion of OOP expenditure in outpatient medical costs decreased by average 0.25 percentage point per month (p <  0.0001) after the intervention, however the proportion of OOP expenditure in inpatient medical costs increased by 0.02 percentage point per month (p = 0.76). Since the intervention, the proportion of medication costs in outpatient medical costs averagely rose by 0.28 percentage point (p <  0.0001), and its implementation caused the proportion of medication costs in inpatient medical costs averagely decreased 0.2 percentage point (p <  0.0001). Conclusions The NMPNP improved the access of anticancer medication, and relieved the financial burden of outpatient care. However, it did not effectively alleviate the financial burden of inpatient care. Additionally, the NMPNP impacted the behavior of the healthcare providers. The policymakers should closely monitor the change of providers behaviors, and dynamically adjust financial incentives policies of healthcare providers during the implementation of similar medication price negotiated policies.
first_indexed 2024-04-13T04:33:56Z
format Article
id doaj.art-2e5d72a3744b45e2abc7f7bb7169c86e
institution Directory Open Access Journal
issn 1471-2458
language English
last_indexed 2024-04-13T04:33:56Z
publishDate 2022-12-01
publisher BMC
record_format Article
series BMC Public Health
spelling doaj.art-2e5d72a3744b45e2abc7f7bb7169c86e2022-12-22T03:02:14ZengBMCBMC Public Health1471-24582022-12-012211910.1186/s12889-022-14525-7The impacts of the National Medication Price-Negotiated Policy on the financial burden of cancer patients in Shandong province, China: an interrupted time series analysisYi Ding0Chao Zheng1Xiaolin Wei2Qi Zhang3Qiang Sun4Center for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong UniversityCenter for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong UniversityDivision of Clinical Public Health and Institute for Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of TorontoDivision of Clinical Public Health and Institute for Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of TorontoCenter for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong UniversityAbstract Background In order to further regulate the price of anticancer medication and alleviate the financial burden of cancer patients, the Chinese government implemented the National Medication Price-Negotiated Policy (NMPNP) in 2017. This study aims to assess the impacts of implementation of the NMPNP on the access of anticancer medication and the financial burden for cancer patients in Shandong province, and to provide evidence to inform the design of similar policies in other developing countries. Methods A quasi-experiment design of an interrupt time series analysis was conducted. The month of September 2017 was taken as the intervention point when the Shandong Provincial Reimbursement Drug Lists was updated based on the result of the NMPNP in 2017. The data used were the aggregated monthly claim data of cancer patients from 2016 to 2021, which were obtained from four cities in Shandong province. The outpatient and inpatient care visits per capita, proportion of OOP expenditure and medication costs in outpatient and inpatient medical costs were used as outcome variables. A segmented regression model was used to analyze the change of the access of anticancer medication and the financial burden for cancer patients. Results The outpatient care visits per capita significantly decreased after the intervention. Compared to preintervention trend, the proportion of OOP expenditure in outpatient medical costs decreased by average 0.25 percentage point per month (p <  0.0001) after the intervention, however the proportion of OOP expenditure in inpatient medical costs increased by 0.02 percentage point per month (p = 0.76). Since the intervention, the proportion of medication costs in outpatient medical costs averagely rose by 0.28 percentage point (p <  0.0001), and its implementation caused the proportion of medication costs in inpatient medical costs averagely decreased 0.2 percentage point (p <  0.0001). Conclusions The NMPNP improved the access of anticancer medication, and relieved the financial burden of outpatient care. However, it did not effectively alleviate the financial burden of inpatient care. Additionally, the NMPNP impacted the behavior of the healthcare providers. The policymakers should closely monitor the change of providers behaviors, and dynamically adjust financial incentives policies of healthcare providers during the implementation of similar medication price negotiated policies.https://doi.org/10.1186/s12889-022-14525-7Price-negotiated policyAnticancer medicationFinancial burdenInterrupted time series analysisChina
spellingShingle Yi Ding
Chao Zheng
Xiaolin Wei
Qi Zhang
Qiang Sun
The impacts of the National Medication Price-Negotiated Policy on the financial burden of cancer patients in Shandong province, China: an interrupted time series analysis
BMC Public Health
Price-negotiated policy
Anticancer medication
Financial burden
Interrupted time series analysis
China
title The impacts of the National Medication Price-Negotiated Policy on the financial burden of cancer patients in Shandong province, China: an interrupted time series analysis
title_full The impacts of the National Medication Price-Negotiated Policy on the financial burden of cancer patients in Shandong province, China: an interrupted time series analysis
title_fullStr The impacts of the National Medication Price-Negotiated Policy on the financial burden of cancer patients in Shandong province, China: an interrupted time series analysis
title_full_unstemmed The impacts of the National Medication Price-Negotiated Policy on the financial burden of cancer patients in Shandong province, China: an interrupted time series analysis
title_short The impacts of the National Medication Price-Negotiated Policy on the financial burden of cancer patients in Shandong province, China: an interrupted time series analysis
title_sort impacts of the national medication price negotiated policy on the financial burden of cancer patients in shandong province china an interrupted time series analysis
topic Price-negotiated policy
Anticancer medication
Financial burden
Interrupted time series analysis
China
url https://doi.org/10.1186/s12889-022-14525-7
work_keys_str_mv AT yiding theimpactsofthenationalmedicationpricenegotiatedpolicyonthefinancialburdenofcancerpatientsinshandongprovincechinaaninterruptedtimeseriesanalysis
AT chaozheng theimpactsofthenationalmedicationpricenegotiatedpolicyonthefinancialburdenofcancerpatientsinshandongprovincechinaaninterruptedtimeseriesanalysis
AT xiaolinwei theimpactsofthenationalmedicationpricenegotiatedpolicyonthefinancialburdenofcancerpatientsinshandongprovincechinaaninterruptedtimeseriesanalysis
AT qizhang theimpactsofthenationalmedicationpricenegotiatedpolicyonthefinancialburdenofcancerpatientsinshandongprovincechinaaninterruptedtimeseriesanalysis
AT qiangsun theimpactsofthenationalmedicationpricenegotiatedpolicyonthefinancialburdenofcancerpatientsinshandongprovincechinaaninterruptedtimeseriesanalysis
AT yiding impactsofthenationalmedicationpricenegotiatedpolicyonthefinancialburdenofcancerpatientsinshandongprovincechinaaninterruptedtimeseriesanalysis
AT chaozheng impactsofthenationalmedicationpricenegotiatedpolicyonthefinancialburdenofcancerpatientsinshandongprovincechinaaninterruptedtimeseriesanalysis
AT xiaolinwei impactsofthenationalmedicationpricenegotiatedpolicyonthefinancialburdenofcancerpatientsinshandongprovincechinaaninterruptedtimeseriesanalysis
AT qizhang impactsofthenationalmedicationpricenegotiatedpolicyonthefinancialburdenofcancerpatientsinshandongprovincechinaaninterruptedtimeseriesanalysis
AT qiangsun impactsofthenationalmedicationpricenegotiatedpolicyonthefinancialburdenofcancerpatientsinshandongprovincechinaaninterruptedtimeseriesanalysis