Aberrant MRP14 expression in thyroid follicular cells mediates chemokine secretion through the IL-1β/MAPK pathway in Hashimoto’s thyroiditis

Aberrant MRP14 expression in thyroid follicular cells mediates chemokine secretion through the IL-1β/MAPK pathway in Hashimoto’s thyroiditis

Myeloid-related protein 14 (MRP14) is responsible for inflammatory reactions. However, the correlation between MRP14 and Hashimoto’s thyroiditis (HT) is still not clear. In this study, we examined the status of MRP14 in thyroid tissues and sera of HT patients and explored the mechanism of IL-1β-medi...

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Bibliographic Details
Main Authors: Xuan Luo, Tingting Zheng, Chaoming Mao, Xin Dong, Xiao Mou, Chengcheng Xu, Qingyan Lu, Baocui Liu, Shengjun Wang, Yichuan Xiao
Format: Article
Language:English
Published: Bioscientifica 2018-06-01
Series:Endocrine Connections
Subjects:
Hashimoto’s thyroiditis
IL-1β/MAPK
MRP14
chemokine
Online Access:http://www.endocrineconnections.com/content/7/6/850.full

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