Chicken DNA Sensing cGAS-STING Signal Pathway Mediates Broad Spectrum Antiviral Functions

Chicken DNA Sensing cGAS-STING Signal Pathway Mediates Broad Spectrum Antiviral Functions

The innate DNA sensing receptors are one family of pattern recognition receptors and play important roles in antiviral infections, especially DNA viral infections. Among the multiple DNA sensors, cGAS has been studied intensively and is most defined in mammals. However, DNA sensors in chickens have...

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Bibliographic Details
Main Authors: Shuangjie Li, Jie Yang, Yuanyuan Zhu, Xingyu Ji, Kun Wang, Sen Jiang, Jia Luo, Hui Wang, Wanglong Zheng, Nanhua Chen, Jianqiang Ye, François Meurens, Jianzhong Zhu
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Vaccines
Subjects:
cGAS-STING
DNA sensors
signaling pathway
antiviral
chicken
Online Access:https://www.mdpi.com/2076-393X/8/3/369

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