Natural and Tumor Induced Regulatory T-cells in Malignant Glioma
One of the hallmark features of glioblastoma multiforme (GBM), the most common adult primary brain tumor with a very dismal prognosis, is the accumulation of CD4+CD25+Foxp3+ regulatory T cells (Tregs). Regulatory T cells (Tregs) segregate into two primary categories: thymus-derived natural Tregs (nT...
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フォーマット: | 論文 |
言語: | English |
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Frontiers Media S.A.
2013-05-01
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シリーズ: | Frontiers in Immunology |
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オンライン・アクセス: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00116/full |