Prediction of hospital mortality after colorectal perforation surgery from inflammation-based prognostic scores
Background: Inflammation-based prognostic scores have prognostic value in cancer or cardiovascular disease patients. This study evaluated the prognostic value of inflammation-based prognostic scores in colorectal perforation patients. Methods: Data of 97 patients who underwent surgery for colorectal...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-04-01
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| Series: | Surgery Open Science |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589845022000021 |
| _version_ | 1818023511554260992 |
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| author | Kensuke Kudou, PhD, MD Tetsuya Kusumoto, PhD, MD Yuho Ebata, MD Sho Nambara, PhD, MD Yasuo Tsuda, PhD, MD Eiji Kusumoto, MD Rintaro Yoshida, PhD, MD Yoshihisa Sakaguchi, PhD, MD Koji Ikejiri, PhD, MD |
| author_facet | Kensuke Kudou, PhD, MD Tetsuya Kusumoto, PhD, MD Yuho Ebata, MD Sho Nambara, PhD, MD Yasuo Tsuda, PhD, MD Eiji Kusumoto, MD Rintaro Yoshida, PhD, MD Yoshihisa Sakaguchi, PhD, MD Koji Ikejiri, PhD, MD |
| author_sort | Kensuke Kudou, PhD, MD |
| collection | DOAJ |
| description | Background: Inflammation-based prognostic scores have prognostic value in cancer or cardiovascular disease patients. This study evaluated the prognostic value of inflammation-based prognostic scores in colorectal perforation patients. Methods: Data of 97 patients who underwent surgery for colorectal perforation were reviewed. We calculated various inflammation-based prognostic scores and analyzed the relationship between inflammation-based prognostic score and hospital mortality due to colorectal perforation. Results: Multivariate analyses of hospital mortality revealed neutrophil–lymphocyte ratio (P = .0021), C-reactive protein/albumin ratio (P = .0224), and prognostic nutritional index (P = .0078) as independent predictive factors. The Kaplan–Meier analysis showed that patients who met all of the following parameters avoided hospital death: neutrophil–lymphocyte ratio < 30, prognostic nutritional index ≥ 27.2, age < 75 years, and perforation of the left colon. Conclusion: Neutrophil–lymphocyte ratio, C-reactive protein/albumin ratio, and prognostic nutritional index were superior to other inflammation-based prognostic scores in predicting mortality of colorectal perforation. Neutrophil–lymphocyte ratio, prognostic nutritional index, patient's age, and sidedness of the perforation site may be useful parameters to identify subgroups in which a favorable prognosis can be expected. |
| first_indexed | 2024-12-10T03:45:29Z |
| format | Article |
| id | doaj.art-2e657748ad7d41bd8a992aa42950cb34 |
| institution | Directory Open Access Journal |
| issn | 2589-8450 |
| language | English |
| last_indexed | 2024-12-10T03:45:29Z |
| publishDate | 2022-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Surgery Open Science |
| spelling | doaj.art-2e657748ad7d41bd8a992aa42950cb342022-12-22T02:03:26ZengElsevierSurgery Open Science2589-84502022-04-0184046Prediction of hospital mortality after colorectal perforation surgery from inflammation-based prognostic scoresKensuke Kudou, PhD, MD0Tetsuya Kusumoto, PhD, MD1Yuho Ebata, MD2Sho Nambara, PhD, MD3Yasuo Tsuda, PhD, MD4Eiji Kusumoto, MD5Rintaro Yoshida, PhD, MD6Yoshihisa Sakaguchi, PhD, MD7Koji Ikejiri, PhD, MD8Corresponding author at: Department of Gastroenterological Surgery, Clinical Research Institute Cancer Research Division National Hospital Organization Kyushu Medical Center, 1-8-1, Jigyohama, Chuo-ku, Fukuoka 810-8563, Japan.; Department of Gastroenterological Surgery, Clinical Research Institute Cancer Research Division, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanDepartment of Gastroenterological Surgery, Clinical Research Institute Cancer Research Division, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanDepartment of Gastroenterological Surgery, Clinical Research Institute Cancer Research Division, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanDepartment of Gastroenterological Surgery, Clinical Research Institute Cancer Research Division, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanDepartment of Gastroenterological Surgery, Clinical Research Institute Cancer Research Division, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanDepartment of Gastroenterological Surgery, Clinical Research Institute Cancer Research Division, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanDepartment of Gastroenterological Surgery, Clinical Research Institute Cancer Research Division, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanDepartment of Gastroenterological Surgery, Clinical Research Institute Cancer Research Division, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanDepartment of Gastroenterological Surgery, Clinical Research Institute Cancer Research Division, National Hospital Organization Kyushu Medical Center, Fukuoka, JapanBackground: Inflammation-based prognostic scores have prognostic value in cancer or cardiovascular disease patients. This study evaluated the prognostic value of inflammation-based prognostic scores in colorectal perforation patients. Methods: Data of 97 patients who underwent surgery for colorectal perforation were reviewed. We calculated various inflammation-based prognostic scores and analyzed the relationship between inflammation-based prognostic score and hospital mortality due to colorectal perforation. Results: Multivariate analyses of hospital mortality revealed neutrophil–lymphocyte ratio (P = .0021), C-reactive protein/albumin ratio (P = .0224), and prognostic nutritional index (P = .0078) as independent predictive factors. The Kaplan–Meier analysis showed that patients who met all of the following parameters avoided hospital death: neutrophil–lymphocyte ratio < 30, prognostic nutritional index ≥ 27.2, age < 75 years, and perforation of the left colon. Conclusion: Neutrophil–lymphocyte ratio, C-reactive protein/albumin ratio, and prognostic nutritional index were superior to other inflammation-based prognostic scores in predicting mortality of colorectal perforation. Neutrophil–lymphocyte ratio, prognostic nutritional index, patient's age, and sidedness of the perforation site may be useful parameters to identify subgroups in which a favorable prognosis can be expected.http://www.sciencedirect.com/science/article/pii/S2589845022000021 |
| spellingShingle | Kensuke Kudou, PhD, MD Tetsuya Kusumoto, PhD, MD Yuho Ebata, MD Sho Nambara, PhD, MD Yasuo Tsuda, PhD, MD Eiji Kusumoto, MD Rintaro Yoshida, PhD, MD Yoshihisa Sakaguchi, PhD, MD Koji Ikejiri, PhD, MD Prediction of hospital mortality after colorectal perforation surgery from inflammation-based prognostic scores Surgery Open Science |
| title | Prediction of hospital mortality after colorectal perforation surgery from inflammation-based prognostic scores |
| title_full | Prediction of hospital mortality after colorectal perforation surgery from inflammation-based prognostic scores |
| title_fullStr | Prediction of hospital mortality after colorectal perforation surgery from inflammation-based prognostic scores |
| title_full_unstemmed | Prediction of hospital mortality after colorectal perforation surgery from inflammation-based prognostic scores |
| title_short | Prediction of hospital mortality after colorectal perforation surgery from inflammation-based prognostic scores |
| title_sort | prediction of hospital mortality after colorectal perforation surgery from inflammation based prognostic scores |
| url | http://www.sciencedirect.com/science/article/pii/S2589845022000021 |
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