Delayed presentation of food protein-induced enterocolitis syndrome (FPIES) to okra in a toddler

Abstract Background Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E (IgE) -mediated food allergy predominantly observed in infants and characterized by the delayed onset of vomiting following ingestion of a trigger food. An increase in research and clinical consideratio...

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Main Authors: Hunter Hall, Sara Anvari, Fallon Schultz, Olubukola Ojuola, Nicholas L. Rider
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Online Access:https://doi.org/10.1186/s13223-024-00871-1
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author Hunter Hall
Sara Anvari
Fallon Schultz
Olubukola Ojuola
Nicholas L. Rider
author_facet Hunter Hall
Sara Anvari
Fallon Schultz
Olubukola Ojuola
Nicholas L. Rider
author_sort Hunter Hall
collection DOAJ
description Abstract Background Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E (IgE) -mediated food allergy predominantly observed in infants and characterized by the delayed onset of vomiting following ingestion of a trigger food. An increase in research and clinical consideration of FPIES has led to the discovery of unique deviations from the standard FPIES triggers and presentations. Case presentation A 34-month-old female patient with a history of consuming okra daily presented to medical attention after developing classic FPIES symptoms to okra beginning at 14-months of age. Conclusions Recently, awareness about the varied nature of FPIES clinical presentation has come to light. This case is the first to describe FPIES to the fruit okra that developed over a 12-month time span after previously tolerating the food. This case serves to emphasize the importance of understanding the range of FPIES symptoms to improve recognition and expedite best practice recommendations.
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spelling doaj.art-2e689afa9a9d483d809fda0ef6cce8a52024-03-05T19:25:16ZengBMCAllergy, Asthma & Clinical Immunology1710-14922024-02-012011410.1186/s13223-024-00871-1Delayed presentation of food protein-induced enterocolitis syndrome (FPIES) to okra in a toddlerHunter Hall0Sara Anvari1Fallon Schultz2Olubukola Ojuola3Nicholas L. Rider4Department of Biology, Liberty UniversityDivision of Immunology, Allergy and Retrovirology, Baylor College of Medicine, Texas Children’s HospitalInternational FPIES AssociationDivision of Pediatrics, Liberty University College of Osteopathic Medicine, Collaborative Health PartnersDepartment of Health System & Implementation Science, Virginia Tech Carilion School of MedicineAbstract Background Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E (IgE) -mediated food allergy predominantly observed in infants and characterized by the delayed onset of vomiting following ingestion of a trigger food. An increase in research and clinical consideration of FPIES has led to the discovery of unique deviations from the standard FPIES triggers and presentations. Case presentation A 34-month-old female patient with a history of consuming okra daily presented to medical attention after developing classic FPIES symptoms to okra beginning at 14-months of age. Conclusions Recently, awareness about the varied nature of FPIES clinical presentation has come to light. This case is the first to describe FPIES to the fruit okra that developed over a 12-month time span after previously tolerating the food. This case serves to emphasize the importance of understanding the range of FPIES symptoms to improve recognition and expedite best practice recommendations.https://doi.org/10.1186/s13223-024-00871-1Food protein-induced enterocolitis syndrome (FPIES)Non-immunoglobulin E (IgE)VomitingOkraFood allergy
spellingShingle Hunter Hall
Sara Anvari
Fallon Schultz
Olubukola Ojuola
Nicholas L. Rider
Delayed presentation of food protein-induced enterocolitis syndrome (FPIES) to okra in a toddler
Allergy, Asthma & Clinical Immunology
Food protein-induced enterocolitis syndrome (FPIES)
Non-immunoglobulin E (IgE)
Vomiting
Okra
Food allergy
title Delayed presentation of food protein-induced enterocolitis syndrome (FPIES) to okra in a toddler
title_full Delayed presentation of food protein-induced enterocolitis syndrome (FPIES) to okra in a toddler
title_fullStr Delayed presentation of food protein-induced enterocolitis syndrome (FPIES) to okra in a toddler
title_full_unstemmed Delayed presentation of food protein-induced enterocolitis syndrome (FPIES) to okra in a toddler
title_short Delayed presentation of food protein-induced enterocolitis syndrome (FPIES) to okra in a toddler
title_sort delayed presentation of food protein induced enterocolitis syndrome fpies to okra in a toddler
topic Food protein-induced enterocolitis syndrome (FPIES)
Non-immunoglobulin E (IgE)
Vomiting
Okra
Food allergy
url https://doi.org/10.1186/s13223-024-00871-1
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