Pancreatic Kininogenase Ameliorates Renal Fibrosis in Streptozotocin Induced-Diabetic Nephropathy Rat

Pancreatic Kininogenase Ameliorates Renal Fibrosis in Streptozotocin Induced-Diabetic Nephropathy Rat

Background/Aims: We aimed to evaluate whether pancreatic kininogenase (PKase) can relieve renal fibrosis and investigate its mechanisms in diabetic nephropathy (DN) rats Methods: We established streptozotocin (STZ) induced-DN rats. After treatment with PKase for 4 weeks, urinary weight, urinary prot...

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Bibliographic Details
Main Authors:	Dan Zhu, Linlin Zhang, Lijuan Cheng, Liansheng Ren, Jie Tang, Dianjun Sun
Format:	Article
Language:	English
Published:	Karger Publishers 2016-01-01
Series:	Kidney & Blood Pressure Research
Subjects:	Transforming growth factor-β1 Pancreatic Kininogenase Renal fibrosis Antizyme inhibitor 1 MiR-433
Online Access:	http://www.karger.com/Article/FullText/368542

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