| Summary: | In this article we presented study results characterizing the lithogenicity changes in cases with biliary tract obstruction based on assessment of lipidic exchange indicators and condition of pro-oxidant – antioxidant activity at the local level. It is determined that in group with primary choledocholithiasis we observed decrease of anti-oxidizing activity by 47.1%, in the absence of reliable changes of intensity for free radical oxidation, rise of general lipids level to 9.9% at simultaneous lack of authentic changes of cholesterol content which are followed by ascending integrated lithogenicity index indicator in average for 59.7%. Besides, it has been shown that in patients with a recurrence of mechanical jaundice (in terms from 2 to 7 months) integrated indicator of lithogenicity index was very high at primary assessment (16.27 U). The possibility to research metabolic disturbances expression for various diseases of a biliopancreatoduodenal area at the local level on the basis of an integrated lithogenicity index indicator allowed to optimize an algorithm for the choice of the biliary tract decompression referred on early endoprosthetic incrustation and also to provide adequate techniques for patients management postoperatively and prove the necessity of performing the certain treatment referred to prophylaxis of the remote complications of endobiliar stenting.
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