Idiopathic intracranial hypertension in a pediatric transgender patient
Purpose: Androgens given for gender affirmation have been implicated in the pathophysiology of idiopathic intracranial hypertension (IIH) in transgender patients. 10 cases of transgender adults with IIH have been published but this association has not been described in younger patients. Herein we de...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993621002176 |
| _version_ | 1818405659827240960 |
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| author | Taylor Nayman Mélanie Hébert Luis H. Ospina |
| author_facet | Taylor Nayman Mélanie Hébert Luis H. Ospina |
| author_sort | Taylor Nayman |
| collection | DOAJ |
| description | Purpose: Androgens given for gender affirmation have been implicated in the pathophysiology of idiopathic intracranial hypertension (IIH) in transgender patients. 10 cases of transgender adults with IIH have been published but this association has not been described in younger patients. Herein we describe the first case of IIH in an adolescent transgender patient. Observations: A 17-year-old non-obese female-to-male transgender patient on subcutaneous testosterone since age 13 presented with a two-month history of transient visual obscuration and frontal headaches. Ophthalmological examination revealed Frisen grade 2 papilledema with preserved visual function. Lumbar puncture confirmed elevated opening pressure. Papilledema resolved with oral acetazolamide and reduction of testosterone therapy. Conclusions and Importance: The use of cross-sex hormone therapy (CSH) for gender affirmation may increase the risk of IIH. Awareness of this association is important as the number of younger transgender patients seeking CSH is increasing significantly. |
| first_indexed | 2024-12-14T08:59:34Z |
| format | Article |
| id | doaj.art-2e7dbfed92c84c7aa407f0bf406fb0b2 |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-12-14T08:59:34Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-2e7dbfed92c84c7aa407f0bf406fb0b22022-12-21T23:08:50ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362021-12-0124101208Idiopathic intracranial hypertension in a pediatric transgender patientTaylor Nayman0Mélanie Hébert1Luis H. Ospina2Department of Ophthalmology, Centre hospitalier universitaire Sainte-Justine, 3175 Chemin de la Côte-Sainte-Catherine, Montréal, QC, H3T 1C5, CanadaFaculty of Medicine, Université de Montréal, 2900 Edouard Montpetit Blvd, Montreal, Quebec, H3T 1J4, CanadaDepartment of Ophthalmology, Centre hospitalier universitaire Sainte-Justine, 3175 Chemin de la Côte-Sainte-Catherine, Montréal, QC, H3T 1C5, Canada; Corresponding author. Department of Ophthalmology, Centre hospitalier universitaire Sainte-Justine, 3175 Chemin de la Côte-Sainte-Catherine, Montreal, Quebec, H3T 1C5, Canada.Purpose: Androgens given for gender affirmation have been implicated in the pathophysiology of idiopathic intracranial hypertension (IIH) in transgender patients. 10 cases of transgender adults with IIH have been published but this association has not been described in younger patients. Herein we describe the first case of IIH in an adolescent transgender patient. Observations: A 17-year-old non-obese female-to-male transgender patient on subcutaneous testosterone since age 13 presented with a two-month history of transient visual obscuration and frontal headaches. Ophthalmological examination revealed Frisen grade 2 papilledema with preserved visual function. Lumbar puncture confirmed elevated opening pressure. Papilledema resolved with oral acetazolamide and reduction of testosterone therapy. Conclusions and Importance: The use of cross-sex hormone therapy (CSH) for gender affirmation may increase the risk of IIH. Awareness of this association is important as the number of younger transgender patients seeking CSH is increasing significantly.http://www.sciencedirect.com/science/article/pii/S2451993621002176Idiopathic intracranial hypertensionPediatricTransgenderHormone therapyAndrogensPapilledema |
| spellingShingle | Taylor Nayman Mélanie Hébert Luis H. Ospina Idiopathic intracranial hypertension in a pediatric transgender patient American Journal of Ophthalmology Case Reports Idiopathic intracranial hypertension Pediatric Transgender Hormone therapy Androgens Papilledema |
| title | Idiopathic intracranial hypertension in a pediatric transgender patient |
| title_full | Idiopathic intracranial hypertension in a pediatric transgender patient |
| title_fullStr | Idiopathic intracranial hypertension in a pediatric transgender patient |
| title_full_unstemmed | Idiopathic intracranial hypertension in a pediatric transgender patient |
| title_short | Idiopathic intracranial hypertension in a pediatric transgender patient |
| title_sort | idiopathic intracranial hypertension in a pediatric transgender patient |
| topic | Idiopathic intracranial hypertension Pediatric Transgender Hormone therapy Androgens Papilledema |
| url | http://www.sciencedirect.com/science/article/pii/S2451993621002176 |
| work_keys_str_mv | AT taylornayman idiopathicintracranialhypertensioninapediatrictransgenderpatient AT melaniehebert idiopathicintracranialhypertensioninapediatrictransgenderpatient AT luishospina idiopathicintracranialhypertensioninapediatrictransgenderpatient |