Context-Specific Genome-Scale Metabolic Modelling and Its Application to the Analysis of COVID-19 Metabolic Signatures

Context-Specific Genome-Scale Metabolic Modelling and Its Application to the Analysis of COVID-19 Metabolic Signatures

Genome-scale metabolic models (GEMs) have found numerous applications in different domains, ranging from biotechnology to systems medicine. Herein, we overview the most popular algorithms for the automated reconstruction of context-specific GEMs using high-throughput experimental data. Moreover, we...

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Bibliographic Details
Main Authors:	Miha Moškon, Tadeja Režen
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Series:	Metabolites
Subjects:	context-specific genome scale metabolic modelling constraint-based modelling omics data integration model extraction method computational pipeline metabolic fluxes
Online Access:	https://www.mdpi.com/2218-1989/13/1/126

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