Vitamin C Improves the Outcomes of Cardiopulmonary Resuscitation and Alters Shedding of Syndecan‐1 and p38/MAPK Phosphorylation in a Rat Model

Vitamin C Improves the Outcomes of Cardiopulmonary Resuscitation and Alters Shedding of Syndecan‐1 and p38/MAPK Phosphorylation in a Rat Model

Background Post‐resuscitation syndrome, involves a severe inflammatory response following successful cardiopulmonary resuscitation. The potential mechanism of Vitamin C (VitC) after cardiopulmonary resuscitation on myocardial and cerebral function, duration of survival is undefined. Methods and Resu...

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Bibliographic Details
Main Authors: Yan Xiao, Chenglei Su, Guozhen Zhang, Lian Liang, Tao Jin, Jennifer Bradley, Joseph P. Ornato, Wanchun Tang
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac arrest
inflammatory cytokines
p38/MAPK pathway
Syndecan‐1
Vitamin C
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.023787

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