BEHCET’S DISEASE IN CHILDREN

Behcet’s disease is a systemic vasculitis with unknown etiology. It is characterized by recurrent erosive and ulcer lesions of mucoustunic of mouth and genitalia, frequent lesions of eyes, joints, gastrointestinal tract and central nervous system. Behcet’s disease arises predominantly in young men i...

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Main Author: Z.S. Alekberova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2009-11-01
Series:Вопросы современной педиатрии
Online Access:https://vsp.spr-journal.ru/jour/article/view/1194
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author Z.S. Alekberova
author_facet Z.S. Alekberova
author_sort Z.S. Alekberova
collection DOAJ
description Behcet’s disease is a systemic vasculitis with unknown etiology. It is characterized by recurrent erosive and ulcer lesions of mucoustunic of mouth and genitalia, frequent lesions of eyes, joints, gastrointestinal tract and central nervous system. Behcet’s disease arises predominantly in young men in the age 20–40 years old; the clinical signs of this disease are forming in children up to the 7–13 years old. Approximately 2–3% of patients with Behcet’s disease are children under 16 years old. The diagnostic criteria of disease, presented in 1990 with International Group of Behcet’s Disease are presented. The comparison of clinical signs of a disease showed bigger frequency of vascular pathology in adults; the rate of HLA-B5 antigen is considerable in children and adults (58,5% and 62,8% accordingly) but an aggregation of disease in families of children with Behcet’s disease is higher (12% vs. 1% in adults). Authors presented EULAR recommendations (2008) on the treatment of Behcet’s disease. The peculiarities of treatment of Behcet’s disease are described.Key words: children, Behcet’s disease, aphthous stomatitis, ulcers of genitalia, uveitis, HLA-B5.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(6):64-70)
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spelling doaj.art-2e89970aa2bc49168748ae843b1dabea2023-09-03T09:16:51Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352009-11-018664701195BEHCET’S DISEASE IN CHILDRENZ.S. Alekberova0НИИ ревматологии РАМН, МоскваBehcet’s disease is a systemic vasculitis with unknown etiology. It is characterized by recurrent erosive and ulcer lesions of mucoustunic of mouth and genitalia, frequent lesions of eyes, joints, gastrointestinal tract and central nervous system. Behcet’s disease arises predominantly in young men in the age 20–40 years old; the clinical signs of this disease are forming in children up to the 7–13 years old. Approximately 2–3% of patients with Behcet’s disease are children under 16 years old. The diagnostic criteria of disease, presented in 1990 with International Group of Behcet’s Disease are presented. The comparison of clinical signs of a disease showed bigger frequency of vascular pathology in adults; the rate of HLA-B5 antigen is considerable in children and adults (58,5% and 62,8% accordingly) but an aggregation of disease in families of children with Behcet’s disease is higher (12% vs. 1% in adults). Authors presented EULAR recommendations (2008) on the treatment of Behcet’s disease. The peculiarities of treatment of Behcet’s disease are described.Key words: children, Behcet’s disease, aphthous stomatitis, ulcers of genitalia, uveitis, HLA-B5.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(6):64-70)https://vsp.spr-journal.ru/jour/article/view/1194
spellingShingle Z.S. Alekberova
BEHCET’S DISEASE IN CHILDREN
Вопросы современной педиатрии
title BEHCET’S DISEASE IN CHILDREN
title_full BEHCET’S DISEASE IN CHILDREN
title_fullStr BEHCET’S DISEASE IN CHILDREN
title_full_unstemmed BEHCET’S DISEASE IN CHILDREN
title_short BEHCET’S DISEASE IN CHILDREN
title_sort behcet s disease in children
url https://vsp.spr-journal.ru/jour/article/view/1194
work_keys_str_mv AT zsalekberova behcetsdiseaseinchildren