Impact of Contraception on Uterine Fibroids
<i>Background and Objectives</i>: Uterine fibroids develop in 25–40% of women of childbearing age; however, there are discrepancies resulting from population and socioeconomic differences. The pathogenesis of fibroids is not clear. The aim of the study was to assess the potential connect...
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MDPI AG
2021-07-01
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| Sarja: | Medicina |
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| Linkit: | https://www.mdpi.com/1648-9144/57/7/717 |
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| author | Katarzyna Kwas Aleksandra Nowakowska Angelika Fornalczyk Magda Krzycka Anna Nowak Jacek Wilczyński Maria Szubert |
| author_facet | Katarzyna Kwas Aleksandra Nowakowska Angelika Fornalczyk Magda Krzycka Anna Nowak Jacek Wilczyński Maria Szubert |
| author_sort | Katarzyna Kwas |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Uterine fibroids develop in 25–40% of women of childbearing age; however, there are discrepancies resulting from population and socioeconomic differences. The pathogenesis of fibroids is not clear. The aim of the study was to assess the potential connection between the use of oral contraceptives and the occurrence of uterine fibroids in women of childbearing age. <i>Materials and Methods</i>: In this prospective, survey, case–control study, data were collected from Caucasian female patients (mean age = 30) using a questionnaire concerning the onset, duration and form of hormonal contraception, and medical and obstetrical history. The questionnaires were handed personally to hospitalized patients as well as distributed through Google forms on social media. <i>Results</i>: In a study group (<i>n</i> = 140) of patients using hormonal contraception, 37.8% of them were diagnosed with uterine fibroids, whereas among the patients not using hormonal contraception (<i>n</i> = 206), uterine fibroids were diagnosed in 59.6% of the patients. The most common hormonal contraception was two-component hormonal tablets used by 93.3% of the patients. Taking contraceptives was a uterine fibroids protective factor (OR = 0.4, <i>p</i> = 0.007). In the study group, 5.5% of the patients were pregnant and 60.42% were diagnosed with uterine fibroids (OR = 4.4, <i>p</i> < 0.000001). <i>Conclusion</i>: Contraception was found to be a protective factor for uterine fibroids among the women surveyed. The presented data confirm the theory about the hormonal dependence of uterine fibroids. |
| first_indexed | 2024-03-10T09:32:13Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-10T09:32:13Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-2e89e7543c15495ca53694a17d3cda3c2023-11-22T04:21:38ZengMDPI AGMedicina1010-660X1648-91442021-07-0157771710.3390/medicina57070717Impact of Contraception on Uterine FibroidsKatarzyna Kwas0Aleksandra Nowakowska1Angelika Fornalczyk2Magda Krzycka3Anna Nowak4Jacek Wilczyński5Maria Szubert6Clinic of Surgical and Oncologic Gynecology, 1st Department of Gynecology and Obstetrics, Medical University of Lodz, M. Pirogow Teaching Hospital, Wilenska 37 St., 94-029 Lodz, PolandClinic of Surgical and Oncologic Gynecology, 1st Department of Gynecology and Obstetrics, Medical University of Lodz, M. Pirogow Teaching Hospital, Wilenska 37 St., 94-029 Lodz, PolandClinic of Surgical and Oncologic Gynecology, 1st Department of Gynecology and Obstetrics, Medical University of Lodz, M. Pirogow Teaching Hospital, Wilenska 37 St., 94-029 Lodz, PolandClinic of Surgical and Oncologic Gynecology, 1st Department of Gynecology and Obstetrics, Medical University of Lodz, M. Pirogow Teaching Hospital, Wilenska 37 St., 94-029 Lodz, PolandClinic of Surgical and Oncologic Gynecology, 1st Department of Gynecology and Obstetrics, Medical University of Lodz, M. Pirogow Teaching Hospital, Wilenska 37 St., 94-029 Lodz, PolandClinic of Surgical and Oncologic Gynecology, 1st Department of Gynecology and Obstetrics, Medical University of Lodz, M. Pirogow Teaching Hospital, Wilenska 37 St., 94-029 Lodz, PolandClinic of Surgical and Oncologic Gynecology, 1st Department of Gynecology and Obstetrics, Medical University of Lodz, M. Pirogow Teaching Hospital, Wilenska 37 St., 94-029 Lodz, Poland<i>Background and Objectives</i>: Uterine fibroids develop in 25–40% of women of childbearing age; however, there are discrepancies resulting from population and socioeconomic differences. The pathogenesis of fibroids is not clear. The aim of the study was to assess the potential connection between the use of oral contraceptives and the occurrence of uterine fibroids in women of childbearing age. <i>Materials and Methods</i>: In this prospective, survey, case–control study, data were collected from Caucasian female patients (mean age = 30) using a questionnaire concerning the onset, duration and form of hormonal contraception, and medical and obstetrical history. The questionnaires were handed personally to hospitalized patients as well as distributed through Google forms on social media. <i>Results</i>: In a study group (<i>n</i> = 140) of patients using hormonal contraception, 37.8% of them were diagnosed with uterine fibroids, whereas among the patients not using hormonal contraception (<i>n</i> = 206), uterine fibroids were diagnosed in 59.6% of the patients. The most common hormonal contraception was two-component hormonal tablets used by 93.3% of the patients. Taking contraceptives was a uterine fibroids protective factor (OR = 0.4, <i>p</i> = 0.007). In the study group, 5.5% of the patients were pregnant and 60.42% were diagnosed with uterine fibroids (OR = 4.4, <i>p</i> < 0.000001). <i>Conclusion</i>: Contraception was found to be a protective factor for uterine fibroids among the women surveyed. The presented data confirm the theory about the hormonal dependence of uterine fibroids.https://www.mdpi.com/1648-9144/57/7/717contraceptionoral contraceptive pillsuterine fibroids |
| spellingShingle | Katarzyna Kwas Aleksandra Nowakowska Angelika Fornalczyk Magda Krzycka Anna Nowak Jacek Wilczyński Maria Szubert Impact of Contraception on Uterine Fibroids Medicina contraception oral contraceptive pills uterine fibroids |
| title | Impact of Contraception on Uterine Fibroids |
| title_full | Impact of Contraception on Uterine Fibroids |
| title_fullStr | Impact of Contraception on Uterine Fibroids |
| title_full_unstemmed | Impact of Contraception on Uterine Fibroids |
| title_short | Impact of Contraception on Uterine Fibroids |
| title_sort | impact of contraception on uterine fibroids |
| topic | contraception oral contraceptive pills uterine fibroids |
| url | https://www.mdpi.com/1648-9144/57/7/717 |
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