Alpha lipoic acid reverses scopolamine-induced spatial memory loss and pyramidal cell neurodegeneration in the prefrontal cortex of Wistar rats

Alpha lipoic acid reverses scopolamine-induced spatial memory loss and pyramidal cell neurodegeneration in the prefrontal cortex of Wistar rats

Neurodegenerative disorders are linked to oxidative tissue damage characterized by gradual loss of cognitive functions and neuronal cells. Alpha-lipoic acid (AHA) has a strong antioxidant property. Scopolamine is an anti-muscarinic agent used to study the mechanism of memory loss in an animal model....

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Bibliographic Details
Main Authors: Adejoke Elizabeth Memudu, Rukky Precious Adanike
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:IBRO Neuroscience Reports
Subjects:
Memory
Scopolamine
Oxidative damage
Alpha lipoic acid
Astrocytes
Chromatolysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242122000355

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