Treatment of skin tumors with intratumoral interleukin 12 gene electrotransfer in the head and neck region: a first-in-human clinical trial protocol

Treatment of skin tumors with intratumoral interleukin 12 gene electrotransfer in the head and neck region: a first-in-human clinical trial protocol

Immune therapies are currently under intensive investigation providing in many cases excellent responses in different tumors. Other possible approach for immunotherapy is a targeted intratumoral delivery of interleukin 12 (IL-12), a cytokine with anti-tumor effectiveness. Due to its immunomodulatory...

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Bibliographic Details
Main Authors: Groselj Ales, Bosnjak Masa, Jesenko Tanja, Cemazar Maja, Markelc Bostjan, Strojan Primoz, Sersa Gregor
Format: Article
Language:English
Published: Sciendo 2022-08-01
Series:Radiology and Oncology
Subjects:
gene therapy
interleukin 12
gene electrotransfer
basal cell carcinoma
head and neck region
Online Access:https://doi.org/10.2478/raon-2022-0021

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