Osteopontin and the C-terminal peptide of thrombospondin-4 compete for CD44 binding and have opposite effects on CD133+ cell colony formation

<p>Abstract</p> <p>Background</p> <p>C21, the C-terminal peptide of thrombospondin-4, has growth promoting activity and was discovered as one of several erythropoietin-dependent endothelial proteins. C21 stimulates red cell formation in anemic mice and is a growth facto...

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Bibliographic Details
Main Authors: Dobocan Monica C, Sadvakassova Gulzhakhan, Congote Luis F
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/2/215