A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers
Abstract Endovascular treatment with stent retriever thrombectomy is a major advancement in the standard of care in acute ischemic stroke (AIS). The modalities through which thrombi embed along stent retriever following mechanical thrombectomy (MTB) have not yet been elucidated. Using scanning elect...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-05-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-11830-4 |
| _version_ | 1828323324901457920 |
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| author | Daniela Dumitriu LaGrange Gianmarco Bernava Philippe Reymond Isabel Wanke Maria Isabel Vargas Paolo Machi Karl-Olof Lövblad |
| author_facet | Daniela Dumitriu LaGrange Gianmarco Bernava Philippe Reymond Isabel Wanke Maria Isabel Vargas Paolo Machi Karl-Olof Lövblad |
| author_sort | Daniela Dumitriu LaGrange |
| collection | DOAJ |
| description | Abstract Endovascular treatment with stent retriever thrombectomy is a major advancement in the standard of care in acute ischemic stroke (AIS). The modalities through which thrombi embed along stent retriever following mechanical thrombectomy (MTB) have not yet been elucidated. Using scanning electron microscopy (SEM), we analyzed the appearance of thrombi retrieved by MTB from AIS patients, when embedded into the stent retriever. We observed that the organization and structural compactness vary for compositionally different thrombi. The modalities of attachment onto the stent vary according to thrombus composition and organization. |
| first_indexed | 2024-04-13T18:50:40Z |
| format | Article |
| id | doaj.art-2e95008b2274439999d4819d69a535f0 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-13T18:50:40Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-2e95008b2274439999d4819d69a535f02022-12-22T02:34:25ZengNature PortfolioScientific Reports2045-23222022-05-0112111110.1038/s41598-022-11830-4A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrieversDaniela Dumitriu LaGrange0Gianmarco Bernava1Philippe Reymond2Isabel Wanke3Maria Isabel Vargas4Paolo Machi5Karl-Olof Lövblad6Neuroradiagnostic and Neurointerventional Division, Department of Radiology and Medical Informatics, Faculty of Medicine, University of GenevaDivision of Diagnostic and Interventional Neuroradiology, HUG Geneva University HospitalsNeuroradiagnostic and Neurointerventional Division, Department of Radiology and Medical Informatics, Faculty of Medicine, University of GenevaDivision of Neuroradiology, Klinik HirslandenNeuroradiagnostic and Neurointerventional Division, Department of Radiology and Medical Informatics, Faculty of Medicine, University of GenevaNeuroradiagnostic and Neurointerventional Division, Department of Radiology and Medical Informatics, Faculty of Medicine, University of GenevaNeuroradiagnostic and Neurointerventional Division, Department of Radiology and Medical Informatics, Faculty of Medicine, University of GenevaAbstract Endovascular treatment with stent retriever thrombectomy is a major advancement in the standard of care in acute ischemic stroke (AIS). The modalities through which thrombi embed along stent retriever following mechanical thrombectomy (MTB) have not yet been elucidated. Using scanning electron microscopy (SEM), we analyzed the appearance of thrombi retrieved by MTB from AIS patients, when embedded into the stent retriever. We observed that the organization and structural compactness vary for compositionally different thrombi. The modalities of attachment onto the stent vary according to thrombus composition and organization.https://doi.org/10.1038/s41598-022-11830-4 |
| spellingShingle | Daniela Dumitriu LaGrange Gianmarco Bernava Philippe Reymond Isabel Wanke Maria Isabel Vargas Paolo Machi Karl-Olof Lövblad A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers Scientific Reports |
| title | A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers |
| title_full | A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers |
| title_fullStr | A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers |
| title_full_unstemmed | A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers |
| title_short | A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers |
| title_sort | high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers |
| url | https://doi.org/10.1038/s41598-022-11830-4 |
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