The high-volume haemodiafiltration vs high-flux haemodialysis registry trial (H4RT): a multi-centre, unblinded, randomised, parallel-group, superiority study to compare the effectiveness and cost-effectiveness of high-volume haemodiafiltration and high-flux haemodialysis in people with kidney failure on maintenance dialysis using linkage to routine healthcare databases for outcomes

The high-volume haemodiafiltration vs high-flux haemodialysis registry trial (H4RT): a multi-centre, unblinded, randomised, parallel-group, superiority study to compare the effectiveness and cost-effectiveness of high-volume haemodiafiltration and high-flux haemodialysis in people with kidney failure on maintenance dialysis using linkage to routine healthcare databases for outcomes

Abstract Background More than a third of the 65,000 people living with kidney failure in the UK attend a dialysis unit 2–5 times a week to have their blood cleaned for 3–5 h. In haemodialysis (HD), toxins are removed by diffusion, which can be enhanced using a high-flux dialyser. This can be augment...

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Bibliographic Details
Main Authors: Fergus J. Caskey, Sunita Procter, Stephanie J. MacNeill, Julia Wade, Jodi Taylor, Leila Rooshenas, Yumeng Liu, Ammar Annaw, Karen Alloway, Andrew Davenport, Albert Power, Ken Farrington, Sandip Mitra, David C. Wheeler, Kristian Law, Helen Lewis-White, Yoav Ben-Shlomo, Will Hollingworth, Jenny Donovan, J. Athene Lane
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Trials
Subjects:
H4RT
Kidney failure
Randomised controlled trial
Haemodialysis
Haemodiafiltration
Integrated qualitative research
Online Access:https://doi.org/10.1186/s13063-022-06357-y

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