Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications

<p>Abstract</p> <p>A uniformly distributed array of micro test tubes and microbeakers is formed on a p-type silicon substrate with tunable cross-section and distance of separation by anodic etching of the silicon wafer in N, N-dimethylformamide and hydrofluoric acid, which essentia...

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Main Authors: Raja Sufi, Dasgupta Anjan, Ghoshal Sarmishtha, Ansar Abul, Jana Arpita, Bandyopadhyay Nil, Ray Mallar
Format: Article
Language:English
Published: SpringerOpen 2011-01-01
Series:Nanoscale Research Letters
Subjects:
Online Access:http://www.nanoscalereslett.com/content/6/1/540
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author Raja Sufi
Dasgupta Anjan
Ghoshal Sarmishtha
Ansar Abul
Jana Arpita
Bandyopadhyay Nil
Ray Mallar
author_facet Raja Sufi
Dasgupta Anjan
Ghoshal Sarmishtha
Ansar Abul
Jana Arpita
Bandyopadhyay Nil
Ray Mallar
author_sort Raja Sufi
collection DOAJ
description <p>Abstract</p> <p>A uniformly distributed array of micro test tubes and microbeakers is formed on a p-type silicon substrate with tunable cross-section and distance of separation by anodic etching of the silicon wafer in N, N-dimethylformamide and hydrofluoric acid, which essentially leads to the formation of macroporous silicon templates. A reasonable control over the dimensions of the structures could be achieved by tailoring the formation parameters, primarily the wafer resistivity. For a micro test tube, the cross-section (i.e., the pore size) as well as the distance of separation between two adjacent test tubes (i.e., inter-pore distance) is typically approximately 1 &#956;m, whereas, for a microbeaker the pore size exceeds 1.5 &#956;m and the inter-pore distance could be less than 100 nm. We successfully synthesized superparamagnetic iron oxide nanoparticles (SPIONs), with average particle size approximately 20 nm and attached them on the porous silicon chip surface as well as on the pore walls. Such SPION-coated arrays of micro test tubes and microbeakers are potential candidates for biosensors because of the biocompatibility of both silicon and SPIONs. As acquisition of data via microarray is an essential attribute of high throughput bio-sensing, the proposed nanostructured array may be a promising step in this direction.</p>
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spelling doaj.art-2e9b00d8871e43af9d31ceb3926cfce92023-09-02T02:34:10ZengSpringerOpenNanoscale Research Letters1931-75731556-276X2011-01-0161540Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applicationsRaja SufiDasgupta AnjanGhoshal SarmishthaAnsar AbulJana ArpitaBandyopadhyay NilRay Mallar<p>Abstract</p> <p>A uniformly distributed array of micro test tubes and microbeakers is formed on a p-type silicon substrate with tunable cross-section and distance of separation by anodic etching of the silicon wafer in N, N-dimethylformamide and hydrofluoric acid, which essentially leads to the formation of macroporous silicon templates. A reasonable control over the dimensions of the structures could be achieved by tailoring the formation parameters, primarily the wafer resistivity. For a micro test tube, the cross-section (i.e., the pore size) as well as the distance of separation between two adjacent test tubes (i.e., inter-pore distance) is typically approximately 1 &#956;m, whereas, for a microbeaker the pore size exceeds 1.5 &#956;m and the inter-pore distance could be less than 100 nm. We successfully synthesized superparamagnetic iron oxide nanoparticles (SPIONs), with average particle size approximately 20 nm and attached them on the porous silicon chip surface as well as on the pore walls. Such SPION-coated arrays of micro test tubes and microbeakers are potential candidates for biosensors because of the biocompatibility of both silicon and SPIONs. As acquisition of data via microarray is an essential attribute of high throughput bio-sensing, the proposed nanostructured array may be a promising step in this direction.</p>http://www.nanoscalereslett.com/content/6/1/540porous siliconSPIONbiosensor
spellingShingle Raja Sufi
Dasgupta Anjan
Ghoshal Sarmishtha
Ansar Abul
Jana Arpita
Bandyopadhyay Nil
Ray Mallar
Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications
Nanoscale Research Letters
porous silicon
SPION
biosensor
title Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications
title_full Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications
title_fullStr Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications
title_full_unstemmed Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications
title_short Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications
title_sort superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p type silicon substrate for biosensor applications
topic porous silicon
SPION
biosensor
url http://www.nanoscalereslett.com/content/6/1/540
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