Checkpoint inhibitors as immunotherapy for fungal infections: Promises, challenges, and unanswered questions

Checkpoint inhibitors as immunotherapy for fungal infections: Promises, challenges, and unanswered questions

Opportunistic fungal infections have high mortality in patients with severe immune dysfunction. Growing evidence suggests that the immune environment of invasive fungal infections and cancers share common features of immune cell exhaustion through activation of immune checkpoint pathways. This obser...

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Bibliographic Details
Main Authors: Sebastian Wurster, Stephanie S. Watowich, Dimitrios P. Kontoyiannis
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
immunotherapy
fungal sepsis
candidiasis
aspergillosis
mucormycosis
checkpoint inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1018202/full

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