The Role of Antibiotics in Breast Pocket Irrigation and Implant Immersion: A Systematic Review
Background:. The usage of antibiotics and antiseptics to washout the breast pocket, or to soak the breast implant during surgery, has come under scrutiny in recent times. Guidelines from the Centers for Disease Control and Prevention give no recommendation for or against the usage of antibiotics in...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2018-09-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001868 |
| _version_ | 1819170293804957696 |
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| author | Ashley O. Frois, B.Eng. Patrick O. Harbour, BBiomedSc Farhad Azimi, MBBS, FRACS, MS Jane Young, MBBS, PhD, FAFPHM Belinda Chan, MBBS (Hons), FRACS, MS Cindy Mak, MBBS (Hons), FRACS Sanjay Warrier, MBBS, FRACS, MS |
| author_facet | Ashley O. Frois, B.Eng. Patrick O. Harbour, BBiomedSc Farhad Azimi, MBBS, FRACS, MS Jane Young, MBBS, PhD, FAFPHM Belinda Chan, MBBS (Hons), FRACS, MS Cindy Mak, MBBS (Hons), FRACS Sanjay Warrier, MBBS, FRACS, MS |
| author_sort | Ashley O. Frois, B.Eng. |
| collection | DOAJ |
| description | Background:. The usage of antibiotics and antiseptics to washout the breast pocket, or to soak the breast implant during surgery, has come under scrutiny in recent times. Guidelines from the Centers for Disease Control and Prevention give no recommendation for or against the usage of antibiotics in this regard. They do however offer a weak recommendation for washing tissues with iodophor. This systematic review aims to investigate the efficacy and impact of such topical antibiotic or antiseptic usage in reducing infection rates.
Methods:. A systematic electronic search was performed on the PreMEDLINE, MEDLINE, EMBASE, and CENTRAL (Cochrane) databases from inception to April 2017. Reference search was performed manually through Scopus. Results of the searches were independently screened by 2 reviewers (A.F. and P.H.). Studies involving an implant or tissue expander, with appropriate controls were included. Meta-analyses were performed where possible and data summarized when not.
Results:. Three retrospective cohort studies were found to fit the review requirements. No randomized control trials were found. These studies covered a period of 1996–2010 for a total of 3,768 women undergoing augmentative surgery. The usage of antibiotics in pocket washout or implant immersion resulted in lower infection rates (RR = 0.52; P = 0.004; 95% CI = 0.34–0.81).
Conclusions:. There is a clinical benefit in using antibiotics for breast pocket irrigation and implant immersion. However, the quality of the evidence obtained in this review is low; hence, we recommend a randomized control trial for a higher level of evidence on this important issue. |
| first_indexed | 2024-12-22T19:33:06Z |
| format | Article |
| id | doaj.art-2ea1488ce75f4c1e83ab485a27acfc14 |
| institution | Directory Open Access Journal |
| issn | 2169-7574 |
| language | English |
| last_indexed | 2024-12-22T19:33:06Z |
| publishDate | 2018-09-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj.art-2ea1488ce75f4c1e83ab485a27acfc142022-12-21T18:15:03ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742018-09-0169e186810.1097/GOX.0000000000001868201809000-00003The Role of Antibiotics in Breast Pocket Irrigation and Implant Immersion: A Systematic ReviewAshley O. Frois, B.Eng.0Patrick O. Harbour, BBiomedSc1Farhad Azimi, MBBS, FRACS, MS2Jane Young, MBBS, PhD, FAFPHM3Belinda Chan, MBBS (Hons), FRACS, MS4Cindy Mak, MBBS (Hons), FRACS5Sanjay Warrier, MBBS, FRACS, MS6From the *Central Clinical School, The University of Sydney, AustraliaFrom the *Central Clinical School, The University of Sydney, Australia†Department of Breast Surgery, Chris O'Brien Lifehouse, Sydney, Australia‡Sydney School of Public Health, University of Sydney, Australia†Department of Breast Surgery, Chris O'Brien Lifehouse, Sydney, Australia†Department of Breast Surgery, Chris O'Brien Lifehouse, Sydney, Australia†Department of Breast Surgery, Chris O'Brien Lifehouse, Sydney, AustraliaBackground:. The usage of antibiotics and antiseptics to washout the breast pocket, or to soak the breast implant during surgery, has come under scrutiny in recent times. Guidelines from the Centers for Disease Control and Prevention give no recommendation for or against the usage of antibiotics in this regard. They do however offer a weak recommendation for washing tissues with iodophor. This systematic review aims to investigate the efficacy and impact of such topical antibiotic or antiseptic usage in reducing infection rates. Methods:. A systematic electronic search was performed on the PreMEDLINE, MEDLINE, EMBASE, and CENTRAL (Cochrane) databases from inception to April 2017. Reference search was performed manually through Scopus. Results of the searches were independently screened by 2 reviewers (A.F. and P.H.). Studies involving an implant or tissue expander, with appropriate controls were included. Meta-analyses were performed where possible and data summarized when not. Results:. Three retrospective cohort studies were found to fit the review requirements. No randomized control trials were found. These studies covered a period of 1996–2010 for a total of 3,768 women undergoing augmentative surgery. The usage of antibiotics in pocket washout or implant immersion resulted in lower infection rates (RR = 0.52; P = 0.004; 95% CI = 0.34–0.81). Conclusions:. There is a clinical benefit in using antibiotics for breast pocket irrigation and implant immersion. However, the quality of the evidence obtained in this review is low; hence, we recommend a randomized control trial for a higher level of evidence on this important issue.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001868 |
| spellingShingle | Ashley O. Frois, B.Eng. Patrick O. Harbour, BBiomedSc Farhad Azimi, MBBS, FRACS, MS Jane Young, MBBS, PhD, FAFPHM Belinda Chan, MBBS (Hons), FRACS, MS Cindy Mak, MBBS (Hons), FRACS Sanjay Warrier, MBBS, FRACS, MS The Role of Antibiotics in Breast Pocket Irrigation and Implant Immersion: A Systematic Review Plastic and Reconstructive Surgery, Global Open |
| title | The Role of Antibiotics in Breast Pocket Irrigation and Implant Immersion: A Systematic Review |
| title_full | The Role of Antibiotics in Breast Pocket Irrigation and Implant Immersion: A Systematic Review |
| title_fullStr | The Role of Antibiotics in Breast Pocket Irrigation and Implant Immersion: A Systematic Review |
| title_full_unstemmed | The Role of Antibiotics in Breast Pocket Irrigation and Implant Immersion: A Systematic Review |
| title_short | The Role of Antibiotics in Breast Pocket Irrigation and Implant Immersion: A Systematic Review |
| title_sort | role of antibiotics in breast pocket irrigation and implant immersion a systematic review |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001868 |
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