Clinical Trial in a Dish: Personalized Stem Cell–Derived Cardiomyocyte Assay Compared With Clinical Trial Results for Two QT‐Prolonging Drugs

Clinical Trial in a Dish: Personalized Stem Cell–Derived Cardiomyocyte Assay Compared With Clinical Trial Results for Two QT‐Prolonging Drugs

Induced pluripotent stem cells (iPSCs) have shown promise in investigating donor‐specific phenotypes and pathologies. The iPSC‐derived cardiomyocytes (iPSC‐CMs) could potentially be utilized in personalized cardiotoxicity studies, assessing individual proarrhythmic risk. However, it is unclear how c...

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Bibliographic Details
Main Authors: Ksenia Blinova, Derek Schocken, Dakshesh Patel, Chathuri Daluwatte, Jose Vicente, Joseph C. Wu, David G. Strauss
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12674

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