Peptide retention time prediction for immobilized artificial membrane phosphatidylcholine stationary phase: method development and preliminary observations

Peptide retention time prediction for immobilized artificial membrane phosphatidylcholine stationary phase: method development and preliminary observations

Development of the first peptide retention prediction model for immobilized artificial membrane phosphatidylcholine (IAM.PC) stationary phase is reported. 2D LC-MS/MS analysis of a whole cell lysate of S. cerevisiae yielded a retention dataset of ~29,500 tryptic peptides; sufficient for confident as...

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Bibliographic Details
Main Authors: Daniel Gussakovsky, Haley Neustaeter, Victor Spicer, Oleg Krokhine
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2018-06-01
Series:ADMET and DMPK
Subjects:
Peptide retention modelling
immobilized artificial membrane chromatography
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/520

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