Systemic effect of tranexamic acid on Prothrombin and clotting times in rabbits after IV injection of heparin (Experimental study)
Aim: To evaluate the effect of a single dose of tranexamic acid (cyclokapron) in reducing the postoperative bleeding following minor oral surgery on ten rabbits on anticoagulant therapy (heparin). Materials and Methods: Samples of blood were collected pre and post heparin and tranexamic acid inje...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Arabic |
| Published: |
University of Mosul, College of Dentistry
2006-06-01
|
| Series: | Al-Rafidain Dental Journal |
| Subjects: | |
| Online Access: | https://rden.mosuljournals.com/pdf_40129_04175f604b6c8ee5d1a7dc79bf794d80.html |
| Summary: | Aim: To evaluate the effect of a single dose of tranexamic acid (cyclokapron) in reducing the
postoperative bleeding following minor oral surgery on ten rabbits on anticoagulant therapy (heparin).
Materials and Methods: Samples of blood were collected pre and post heparin and tranexamic acid
injection for measuring the Prothrombin and clotting time. Results: There was no significant difference
between the Prothrombin time and clotting time normal and Prothrombin time and clotting time after
tranexamic acid injection. Conclusion: A single dose of tranexamic acid given postoperatively was
effective in reducing the postoperative bleeding following minor oral surgery in experimental rabbit on
heparin anticoagulant therapy without changing the regular heparin regimen doses. The same regimen
may be applied on hospitalized patient on heparin anticoagulant therapy |
|---|---|
| ISSN: | 1812-1217 1998-0345 |