Resistant ovary syndrome: Pathogenesis and management strategies
Resistant ovary syndrome (ROS) is a rare and difficult gynecological endocrine disorder that poses a serious risk to women’s reproductive health. The clinical features are normal sex characteristics, regular female karyotype, and usual ovarian reserve, but elevated endogenous gonadotropin levels and...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-10-01
|
| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.1030004/full |
| _version_ | 1797986150319652864 |
|---|---|
| author | Zhenni Mu Sinan Shen Lei Lei |
| author_facet | Zhenni Mu Sinan Shen Lei Lei |
| author_sort | Zhenni Mu |
| collection | DOAJ |
| description | Resistant ovary syndrome (ROS) is a rare and difficult gynecological endocrine disorder that poses a serious risk to women’s reproductive health. The clinical features are normal sex characteristics, regular female karyotype, and usual ovarian reserve, but elevated endogenous gonadotropin levels and low estrogen levels with primary or secondary amenorrhea. Although there have been many case reports of the disease over the past 50 years, the pathogenesis of the disease is still poorly understood, and there are still no effective clinical management strategies. In this review, we have collected all the current reports on ROS and summarized the pathogenesis and treatment strategies for this disease, intending to provide some clinical references for the management and treatment of this group of patients and provide the foothold for future studies. |
| first_indexed | 2024-04-11T07:29:29Z |
| format | Article |
| id | doaj.art-2eb128ca41424f37b96400f6302d47cf |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-11T07:29:29Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-2eb128ca41424f37b96400f6302d47cf2022-12-22T04:36:57ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-10-01910.3389/fmed.2022.10300041030004Resistant ovary syndrome: Pathogenesis and management strategiesZhenni MuSinan ShenLei LeiResistant ovary syndrome (ROS) is a rare and difficult gynecological endocrine disorder that poses a serious risk to women’s reproductive health. The clinical features are normal sex characteristics, regular female karyotype, and usual ovarian reserve, but elevated endogenous gonadotropin levels and low estrogen levels with primary or secondary amenorrhea. Although there have been many case reports of the disease over the past 50 years, the pathogenesis of the disease is still poorly understood, and there are still no effective clinical management strategies. In this review, we have collected all the current reports on ROS and summarized the pathogenesis and treatment strategies for this disease, intending to provide some clinical references for the management and treatment of this group of patients and provide the foothold for future studies.https://www.frontiersin.org/articles/10.3389/fmed.2022.1030004/fullresistant ovary syndromeetiologypathogenesisinfertilitymanagement strategies |
| spellingShingle | Zhenni Mu Sinan Shen Lei Lei Resistant ovary syndrome: Pathogenesis and management strategies Frontiers in Medicine resistant ovary syndrome etiology pathogenesis infertility management strategies |
| title | Resistant ovary syndrome: Pathogenesis and management strategies |
| title_full | Resistant ovary syndrome: Pathogenesis and management strategies |
| title_fullStr | Resistant ovary syndrome: Pathogenesis and management strategies |
| title_full_unstemmed | Resistant ovary syndrome: Pathogenesis and management strategies |
| title_short | Resistant ovary syndrome: Pathogenesis and management strategies |
| title_sort | resistant ovary syndrome pathogenesis and management strategies |
| topic | resistant ovary syndrome etiology pathogenesis infertility management strategies |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.1030004/full |
| work_keys_str_mv | AT zhennimu resistantovarysyndromepathogenesisandmanagementstrategies AT sinanshen resistantovarysyndromepathogenesisandmanagementstrategies AT leilei resistantovarysyndromepathogenesisandmanagementstrategies |