Numerical modelling of the dissolution of drug nanocrystals and its application to industrial product development

Numerical modelling of the dissolution of drug nanocrystals and its application to industrial product development

The apparent solubility of drug nanocrystals in equilibrium was experimentally determined for a drug-stabilizer system with different particle size distributions. True supersaturation was identified for ultrafine drug nanocrystals with an almost 2-fold increase compared to the thermodynamic solubil...

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Bibliografische gegevens
Hoofdauteurs:	Bastian Bonhoeffer, Andreas Kordikowski, Edgar John, Michael Juhnke
Formaat:	Artikel
Taal:	English
Gepubliceerd in:	International Association of Physical Chemists (IAPC) 2022-08-01
Reeks:	ADMET and DMPK
Online toegang:	https://pub.iapchem.org/ojs/index.php/admet/article/view/1437

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