Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings
Retinal findings may change in patients with obstructive sleep apnea syndrome (OSAS). The present study aims to evaluate several retinal findings, such as macula layer thickness, the peripapillary retinal nerve fiber layer, and the optic nerve head in patients with OSAS, using optical coherence tomo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/3/815 |
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| author | Gloria Tejero-Garcés Francisco J. Ascaso Paula Casas Maria I. Adiego Peter Baptista Carlos O’Connor-Reina Eugenio Vicente Guillermo Plaza |
| author_facet | Gloria Tejero-Garcés Francisco J. Ascaso Paula Casas Maria I. Adiego Peter Baptista Carlos O’Connor-Reina Eugenio Vicente Guillermo Plaza |
| author_sort | Gloria Tejero-Garcés |
| collection | DOAJ |
| description | Retinal findings may change in patients with obstructive sleep apnea syndrome (OSAS). The present study aims to evaluate several retinal findings, such as macula layer thickness, the peripapillary retinal nerve fiber layer, and the optic nerve head in patients with OSAS, using optical coherence tomography (OCT); it also aims to monitor the result of several types of treatment of OSAS with OCT. A prospective comparative study was designed. Patients were recruited at a Sleep Unit of a University Hospital and underwent comprehensive ophthalmological examinations. Following exclusion criteria, fifty-two patients with OSAS were finally included. Patients were examined by OCT twice: once before treatment, and again after six months of treatment. In mild–moderate patients, where retinal swelling had been demonstrated, retinal thicknesses decreased [fovea (<i>p</i> = 0.026), as did inner ring macula (<i>p</i> = 0.007), outer ring macula (<i>p</i> = 0.015), and macular volume (<i>p</i> = 0.015)]. In severe patients, where retinal atrophy had been observed, retinal thickness increased [fovea (<i>p</i> < 0.001)]. No statistically significant differences in efficacy between treatments were demonstrated. In conclusion, OCT can evaluate the retina in patients with OSAS and help to monitor results after treatment. In severe OSAS, retinal thickness increased six months after treatment. |
| first_indexed | 2024-03-09T23:39:42Z |
| format | Article |
| id | doaj.art-2eba5c92fd424e2081f3032ff910da3a |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T23:39:42Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-2eba5c92fd424e2081f3032ff910da3a2023-11-23T16:54:27ZengMDPI AGJournal of Clinical Medicine2077-03832022-02-0111381510.3390/jcm11030815Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal FindingsGloria Tejero-Garcés0Francisco J. Ascaso1Paula Casas2Maria I. Adiego3Peter Baptista4Carlos O’Connor-Reina5Eugenio Vicente6Guillermo Plaza7Department of Otolaryngology, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, SpainDepartment of Ophthalmology, Lozano Blesa University Clinic Hospital, 50009 Zaragoza, SpainDepartment of Ophthalmology, Lozano Blesa University Clinic Hospital, 50009 Zaragoza, SpainDepartment of Otolaryngology, Hospital Universitario Miguel Servet, 50009 Zaragoza, SpainDepartment of Otolaryngology, Clínica Universitaria de Navarra, 31008 Pamplona, SpainDepartment of Otolaryngology, Hospital Quironsalud Marbella, 29603 Marbella, SpainDepartment of Otolaryngology, Hospital Universitario Miguel Servet, 50009 Zaragoza, SpainDepartment of Otolaryngology, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos, 28942 Madrid, SpainRetinal findings may change in patients with obstructive sleep apnea syndrome (OSAS). The present study aims to evaluate several retinal findings, such as macula layer thickness, the peripapillary retinal nerve fiber layer, and the optic nerve head in patients with OSAS, using optical coherence tomography (OCT); it also aims to monitor the result of several types of treatment of OSAS with OCT. A prospective comparative study was designed. Patients were recruited at a Sleep Unit of a University Hospital and underwent comprehensive ophthalmological examinations. Following exclusion criteria, fifty-two patients with OSAS were finally included. Patients were examined by OCT twice: once before treatment, and again after six months of treatment. In mild–moderate patients, where retinal swelling had been demonstrated, retinal thicknesses decreased [fovea (<i>p</i> = 0.026), as did inner ring macula (<i>p</i> = 0.007), outer ring macula (<i>p</i> = 0.015), and macular volume (<i>p</i> = 0.015)]. In severe patients, where retinal atrophy had been observed, retinal thickness increased [fovea (<i>p</i> < 0.001)]. No statistically significant differences in efficacy between treatments were demonstrated. In conclusion, OCT can evaluate the retina in patients with OSAS and help to monitor results after treatment. In severe OSAS, retinal thickness increased six months after treatment.https://www.mdpi.com/2077-0383/11/3/815retinaretinal nerve fiber layerobstructive sleep apnea syndromeoptical coherence tomographyOCTCPAP |
| spellingShingle | Gloria Tejero-Garcés Francisco J. Ascaso Paula Casas Maria I. Adiego Peter Baptista Carlos O’Connor-Reina Eugenio Vicente Guillermo Plaza Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings Journal of Clinical Medicine retina retinal nerve fiber layer obstructive sleep apnea syndrome optical coherence tomography OCT CPAP |
| title | Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings |
| title_full | Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings |
| title_fullStr | Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings |
| title_full_unstemmed | Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings |
| title_short | Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings |
| title_sort | assessment of the effectiveness of obstructive sleep apnea treatment using optical coherence tomography to evaluate retinal findings |
| topic | retina retinal nerve fiber layer obstructive sleep apnea syndrome optical coherence tomography OCT CPAP |
| url | https://www.mdpi.com/2077-0383/11/3/815 |
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