Does clozapine induce myocarditis, myocardial oxidative stress and DNA damage in rats?

Clozapine is an atypical antipsychotic drug selectively effective in the treatment of refractory schizophrenia. However, myocarditis, as a serious cardiotoxic effect, has in several case reports been associated with clozapine therapy. Ani increase in the free radical production and ischemia, probabl...

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Bibliographic Details
Main Authors: Basel A. Abdel-Wahab, Metwally E. Abdalla, Mohamed M. El-khawanki
Format: Article
Language:English
Published: SpringerOpen 2014-09-01
Series:Egyptian Journal of Forensic Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2090536X14000227