Efficacy of Selective Laser Trabeculoplasty in Primary Angle-Closure Glaucoma after peripheral iridotomy: a long-term follow-up
Purpose. To evaluate an efficiency of selective laser trabeculoplasty (SLT) in treatment of patients with primary angle closure glaucoma (PACG) following a YAG laser peripheral iridotomy (PI) compared with primary open angle glaucoma (POAG) in long-term follow-up period.Material and methods. The SLT...
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| Format: | Article |
| Language: | Russian |
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Publishing house "Ophthalmology"
2018-11-01
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| Series: | Офтальмохирургия |
| Subjects: | |
| Online Access: | https://www.ophthalmosurgery.ru/jour/article/view/436 |
| _version_ | 1797946619888402432 |
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| author | N. I. Kurysheva L. V. Lepeshkina E. O. Shatalova |
| author_facet | N. I. Kurysheva L. V. Lepeshkina E. O. Shatalova |
| author_sort | N. I. Kurysheva |
| collection | DOAJ |
| description | Purpose. To evaluate an efficiency of selective laser trabeculoplasty (SLT) in treatment of patients with primary angle closure glaucoma (PACG) following a YAG laser peripheral iridotomy (PI) compared with primary open angle glaucoma (POAG) in long-term follow-up period.Material and methods. The SLT hypotensive efficiency was evaluated in 68 eyes with the initial PACG after PI performed not earlier than one month before SLT and in 74 eyes with initial POAG. The quantity of necessary hypotensive medication to decrease IOP ≤21 mm was also considered. Rate of progression (ROP) of glaucoma optic neuropathy was assessed using the MD index, RNFL and GCC thickness. Follow-up period lasted 6 years.Results. The IOP was decreased significantly after SLT in both groups in long-term period. However, hypotensive effect was more pronounced in PACG – 41.18% compared to POAG – 28.38%. After 6 years, a significantly less quantity of hypotensive eye drops was required to achieve a hypotensive efficacy in PACG than in POAG: 0.68±0.92 and 1.18±0.75, respectively (р=0.035). There was no significant difference in ROP between PACG and POAG: -0.06±0.65 dB/year and -0.14±0.48 dB/year, respectively for MD (р=0.461); -0.57±1.82 μm/year and -0.62±1.59 μm/year for RNFL (р=0.372); -0.60±2.36 μm/year and -0.71±1.98 μm/ year for GCC (р=0.292).Conclusion. The SLT is a safe and effective laser treatment method for the initial stage of PACG after peripheral laser iridotomy. Hypotensive effect of SLT in case of PACG is higher than in POAG, especially 2 and 6 years after the procedure. The SLT in the initial stages of POAG and PACG allows to stabilize glaucoma optic neuropathy. |
| first_indexed | 2024-04-10T21:13:56Z |
| format | Article |
| id | doaj.art-2ebe176e35b340d187383be81846cad9 |
| institution | Directory Open Access Journal |
| issn | 0235-4160 2312-4970 |
| language | Russian |
| last_indexed | 2024-04-10T21:13:56Z |
| publishDate | 2018-11-01 |
| publisher | Publishing house "Ophthalmology" |
| record_format | Article |
| series | Офтальмохирургия |
| spelling | doaj.art-2ebe176e35b340d187383be81846cad92023-01-20T12:34:52ZrusPublishing house "Ophthalmology"Офтальмохирургия0235-41602312-49702018-11-0103334010.25276/0235-4160-2018-3-33-40361Efficacy of Selective Laser Trabeculoplasty in Primary Angle-Closure Glaucoma after peripheral iridotomy: a long-term follow-upN. I. Kurysheva0L. V. Lepeshkina1E. O. Shatalova2The Ophthalmologic al Center of the Federal Medical and Biological Agency Institute of Advanced Training of Federal Medical and Biological Agency , the Chair of OphthalmologyThe Ophthalmologic al Center of the Federal Medical and Biological Agency Institute of Advanced Training of Federal Medical and Biological Agency , the Chair of OphthalmologyThe Dr . Shatalov Clinics, Moscow r egionPurpose. To evaluate an efficiency of selective laser trabeculoplasty (SLT) in treatment of patients with primary angle closure glaucoma (PACG) following a YAG laser peripheral iridotomy (PI) compared with primary open angle glaucoma (POAG) in long-term follow-up period.Material and methods. The SLT hypotensive efficiency was evaluated in 68 eyes with the initial PACG after PI performed not earlier than one month before SLT and in 74 eyes with initial POAG. The quantity of necessary hypotensive medication to decrease IOP ≤21 mm was also considered. Rate of progression (ROP) of glaucoma optic neuropathy was assessed using the MD index, RNFL and GCC thickness. Follow-up period lasted 6 years.Results. The IOP was decreased significantly after SLT in both groups in long-term period. However, hypotensive effect was more pronounced in PACG – 41.18% compared to POAG – 28.38%. After 6 years, a significantly less quantity of hypotensive eye drops was required to achieve a hypotensive efficacy in PACG than in POAG: 0.68±0.92 and 1.18±0.75, respectively (р=0.035). There was no significant difference in ROP between PACG and POAG: -0.06±0.65 dB/year and -0.14±0.48 dB/year, respectively for MD (р=0.461); -0.57±1.82 μm/year and -0.62±1.59 μm/year for RNFL (р=0.372); -0.60±2.36 μm/year and -0.71±1.98 μm/ year for GCC (р=0.292).Conclusion. The SLT is a safe and effective laser treatment method for the initial stage of PACG after peripheral laser iridotomy. Hypotensive effect of SLT in case of PACG is higher than in POAG, especially 2 and 6 years after the procedure. The SLT in the initial stages of POAG and PACG allows to stabilize glaucoma optic neuropathy.https://www.ophthalmosurgery.ru/jour/article/view/436selective laser trabeculoplastyprimary angle closure glaucomaprimary open angle glaucomaglaucoma pr ogression |
| spellingShingle | N. I. Kurysheva L. V. Lepeshkina E. O. Shatalova Efficacy of Selective Laser Trabeculoplasty in Primary Angle-Closure Glaucoma after peripheral iridotomy: a long-term follow-up Офтальмохирургия selective laser trabeculoplasty primary angle closure glaucoma primary open angle glaucoma glaucoma pr ogression |
| title | Efficacy of Selective Laser Trabeculoplasty in Primary Angle-Closure Glaucoma after peripheral iridotomy: a long-term follow-up |
| title_full | Efficacy of Selective Laser Trabeculoplasty in Primary Angle-Closure Glaucoma after peripheral iridotomy: a long-term follow-up |
| title_fullStr | Efficacy of Selective Laser Trabeculoplasty in Primary Angle-Closure Glaucoma after peripheral iridotomy: a long-term follow-up |
| title_full_unstemmed | Efficacy of Selective Laser Trabeculoplasty in Primary Angle-Closure Glaucoma after peripheral iridotomy: a long-term follow-up |
| title_short | Efficacy of Selective Laser Trabeculoplasty in Primary Angle-Closure Glaucoma after peripheral iridotomy: a long-term follow-up |
| title_sort | efficacy of selective laser trabeculoplasty in primary angle closure glaucoma after peripheral iridotomy a long term follow up |
| topic | selective laser trabeculoplasty primary angle closure glaucoma primary open angle glaucoma glaucoma pr ogression |
| url | https://www.ophthalmosurgery.ru/jour/article/view/436 |
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