Phylogenetic Gaussian process model for the inference of functionally important regions in protein tertiary structures.

A critical question in biology is the identification of functionally important amino acid sites in proteins. Because functionally important sites are under stronger purifying selection, site-specific substitution rates tend to be lower than usual at these sites. A large number of phylogenetic models...

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Xehetasun bibliografikoak
Egile Nagusiak: Yi-Fei Huang, G Brian Golding
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Public Library of Science (PLoS) 2014-01-01
Saila:PLoS Computational Biology
Sarrera elektronikoa:http://europepmc.org/articles/PMC3894161?pdf=render

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