Thermal stress impaired expression of insulin-like growth factor binding proteins in pigs
This study aimed to investigate the correlation of IGFs, IGFBPs, and IGFBPRs of grower pigs with change in temperature humidity index (THI). THI was calculated to know the months of the year when pigs feel discomfort and samples of feed offered were analyzed to know the nutritional availability/def...
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| Format: | Article |
| Language: | English |
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Indian Council of Agricultural Research
2023-04-01
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| Series: | Indian Journal of Animal Sciences |
| Subjects: | |
| Online Access: | https://epubs.icar.org.in/index.php/IJAnS/article/view/128685 |
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| author | S BORAH S SOREN R TALUKDAR L KALITA K PAME A J NATH B BORAH P K PATHAK B N BHATTACHARRYYA |
| author_facet | S BORAH S SOREN R TALUKDAR L KALITA K PAME A J NATH B BORAH P K PATHAK B N BHATTACHARRYYA |
| author_sort | S BORAH |
| collection | DOAJ |
| description |
This study aimed to investigate the correlation of IGFs, IGFBPs, and IGFBPRs of grower pigs with change in temperature humidity index (THI). THI was calculated to know the months of the year when pigs feel discomfort and samples of feed offered were analyzed to know the nutritional availability/deficit. The calculated average THI was above thermal comfort zone for seven months in a year. It was observed that crude protein (CP) and metabolizable energy (ME) availability to pigs were deficient. Gilts of two months age and similar body weight were randomly divided into two groups (n=6); viz. Con-fed animals (feed offered by the farmer) and For-fed animals (formulated feed supplement + Con-fed). The composition of formulated feed supplement was dried leaf of Moringa oleifera, soybean meal, rice mill waste, and mineral mixture. The plasma cortisol level increased in the experimental animals with accelerated THI as evidenced by the strong positive correlation of THI with HSP70 and HSP90. The level of leptin and ghrelin did not have significant relation with the expression level of HSPs in the present study, however, in the control animals, a low level of leptin was observed. The correlation between the growth factors and HSPs was not significant. During the season, where the THI was above the thermal comfort zone, the IGFBPR and IGFBP concentrations were non-significantly increased along with the increased THI.
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| first_indexed | 2024-04-09T18:19:41Z |
| format | Article |
| id | doaj.art-2ecb24f00d3e4c58a8164a7f428ec96a |
| institution | Directory Open Access Journal |
| issn | 0367-8318 2394-3327 |
| language | English |
| last_indexed | 2024-04-09T18:19:41Z |
| publishDate | 2023-04-01 |
| publisher | Indian Council of Agricultural Research |
| record_format | Article |
| series | Indian Journal of Animal Sciences |
| spelling | doaj.art-2ecb24f00d3e4c58a8164a7f428ec96a2023-04-12T08:37:09ZengIndian Council of Agricultural ResearchIndian Journal of Animal Sciences0367-83182394-33272023-04-0193310.56093/ijans.v93i3.128685Thermal stress impaired expression of insulin-like growth factor binding proteins in pigsS BORAH0S SOREN1R TALUKDAR2L KALITA3K PAME4A J NATH5B BORAH6P K PATHAK7B N BHATTACHARRYYA8Lakhimpur College of Veterinary Science, Assam Agricultural University, North Lakhimpur, AssamLakhimpur College of Veterinary Science, Assam Agricultural University, North Lakhimpur, AssamCollege of Veterinary Science, Assam Agricultural University, Guwahati, AssamKamrup Polytechnic, Baihata Chariali, Kamrup, AssamLakhimpur College of Veterinary Science, Assam Agricultural University, North Lakhimpur, AssamLakhimpur College of Veterinary Science, Assam Agricultural University, North Lakhimpur, AssamLakhimpur College of Veterinary Science, Assam Agricultural University, North Lakhimpur, AssamKVK, Assam Agricultural University, North Lakhimpur, AssamCollege of Veterinary Science, Assam Agricultural University, Guwahati, Assam This study aimed to investigate the correlation of IGFs, IGFBPs, and IGFBPRs of grower pigs with change in temperature humidity index (THI). THI was calculated to know the months of the year when pigs feel discomfort and samples of feed offered were analyzed to know the nutritional availability/deficit. The calculated average THI was above thermal comfort zone for seven months in a year. It was observed that crude protein (CP) and metabolizable energy (ME) availability to pigs were deficient. Gilts of two months age and similar body weight were randomly divided into two groups (n=6); viz. Con-fed animals (feed offered by the farmer) and For-fed animals (formulated feed supplement + Con-fed). The composition of formulated feed supplement was dried leaf of Moringa oleifera, soybean meal, rice mill waste, and mineral mixture. The plasma cortisol level increased in the experimental animals with accelerated THI as evidenced by the strong positive correlation of THI with HSP70 and HSP90. The level of leptin and ghrelin did not have significant relation with the expression level of HSPs in the present study, however, in the control animals, a low level of leptin was observed. The correlation between the growth factors and HSPs was not significant. During the season, where the THI was above the thermal comfort zone, the IGFBPR and IGFBP concentrations were non-significantly increased along with the increased THI. https://epubs.icar.org.in/index.php/IJAnS/article/view/128685Binding proteins, Grower pigs, Insulin-like growth factors, Receptors,Temperature humidity index |
| spellingShingle | S BORAH S SOREN R TALUKDAR L KALITA K PAME A J NATH B BORAH P K PATHAK B N BHATTACHARRYYA Thermal stress impaired expression of insulin-like growth factor binding proteins in pigs Indian Journal of Animal Sciences Binding proteins, Grower pigs, Insulin-like growth factors, Receptors,Temperature humidity index |
| title | Thermal stress impaired expression of insulin-like growth factor binding proteins in pigs |
| title_full | Thermal stress impaired expression of insulin-like growth factor binding proteins in pigs |
| title_fullStr | Thermal stress impaired expression of insulin-like growth factor binding proteins in pigs |
| title_full_unstemmed | Thermal stress impaired expression of insulin-like growth factor binding proteins in pigs |
| title_short | Thermal stress impaired expression of insulin-like growth factor binding proteins in pigs |
| title_sort | thermal stress impaired expression of insulin like growth factor binding proteins in pigs |
| topic | Binding proteins, Grower pigs, Insulin-like growth factors, Receptors,Temperature humidity index |
| url | https://epubs.icar.org.in/index.php/IJAnS/article/view/128685 |
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