Parallel Propagation of <i>Toxoplasma gondii</i> In Vivo, In Vitro and in Alternate Model: Towards Less Dependence on the Mice Model

Parallel Propagation of <i>Toxoplasma gondii</i> In Vivo, In Vitro and in Alternate Model: Towards Less Dependence on the Mice Model

<i>Toxoplasma gondii</i> is an obligate intracellular protozoan. In pregnant women, it can lead to severe birth defects or intrauterine death of the fetus. Most of what is currently know on cell biology of <i>T. gondii</i> comes from studies relying on the RH strain propagate...

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Bibliographic Details
Main Authors: Maria João Gargaté, Anabela Vilares, Idalina Ferreira, Tânia Reis, Susana Martins, Joana Mendonça, Vítor Borges, João Paulo Gomes
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pathogens
Subjects:
<i>Toxoplasma gondii</i>
3Rs
strain propagation
mice model
in vitro propagation
virulence
Online Access:https://www.mdpi.com/2076-0817/11/9/1038

Internet

https://www.mdpi.com/2076-0817/11/9/1038

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