Suppression of metastatic organ colonization and antiangiogenic activity of the orally bioavailable lipid raft-targeted alkylphospholipid edelfosine
Metastasis is the leading cause of cancer mortality. Metastatic cancer is notoriously difficult to treat, and it accounts for the majority of cancer-related deaths. The ether lipid edelfosine is the prototype of a family of synthetic antitumor compounds collectively known as alkylphospholipid analog...
Main Authors: | Verónica Alonso-Pérez, Vanessa Hernández, Marco A. Calzado, Alba Vicente-Blázquez, Consuelo Gajate, Rafael Soler-Torronteras, Kathleen DeCicco-Skinner, Angels Sierra, Faustino Mollinedo |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-02-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332224000301 |
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