Suppression of metastatic organ colonization and antiangiogenic activity of the orally bioavailable lipid raft-targeted alkylphospholipid edelfosine

Metastasis is the leading cause of cancer mortality. Metastatic cancer is notoriously difficult to treat, and it accounts for the majority of cancer-related deaths. The ether lipid edelfosine is the prototype of a family of synthetic antitumor compounds collectively known as alkylphospholipid analog...

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Main Authors: Verónica Alonso-Pérez, Vanessa Hernández, Marco A. Calzado, Alba Vicente-Blázquez, Consuelo Gajate, Rafael Soler-Torronteras, Kathleen DeCicco-Skinner, Angels Sierra, Faustino Mollinedo
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Biomedicine & Pharmacotherapy
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Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224000301

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