Primary lymphoma of the breast: A case report and review of the literature
Primary lymphoma of the breast is a rare disease, accounting for about 0.5% of all primary breast tumors. Often found as a solitary indolent mass, it is difficult to distinguish from breast cancer on imaging and is often diagnosed for the first time based on histological findings. Diffuse large B-ce...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043320305574 |
| _version_ | 1831735281166843904 |
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| author | Kimiyasu Yoneyama, MD Motohito Nakagawa, MD,PhD Asuka Hara, MD |
| author_facet | Kimiyasu Yoneyama, MD Motohito Nakagawa, MD,PhD Asuka Hara, MD |
| author_sort | Kimiyasu Yoneyama, MD |
| collection | DOAJ |
| description | Primary lymphoma of the breast is a rare disease, accounting for about 0.5% of all primary breast tumors. Often found as a solitary indolent mass, it is difficult to distinguish from breast cancer on imaging and is often diagnosed for the first time based on histological findings. Diffuse large B-cell lymphoma is the most common histological subtype. A 48-year-old woman visited our hospital because of a painless mass in the left breast. Breast cancer was suspected based on the imaging findings. A core needle biopsy was performed, and the invasive ductal carcinoma was diagnosed. Partial mastectomy and sentinel lymph node biopsy were performed. The resected specimen was finally diagnosed as diffuse large B-cell lymphoma based on immunohistochemical staining. The patient was treated with R-CHOP and intrathecal injection of methotrexate. The patient remains alive without recurrence 4 years later. Awareness of primary breast lymphoma is essential for accurate and timely diagnosis and avoidance of unnecessary surgery. |
| first_indexed | 2024-12-21T12:23:19Z |
| format | Article |
| id | doaj.art-2eccbad876b947b08ec8ee8b75ff6c2e |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-21T12:23:19Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-2eccbad876b947b08ec8ee8b75ff6c2e2022-12-21T19:04:14ZengElsevierRadiology Case Reports1930-04332021-01-011615561Primary lymphoma of the breast: A case report and review of the literatureKimiyasu Yoneyama, MD0Motohito Nakagawa, MD,PhD1Asuka Hara, MD2Corresponding author.; Department of Breast Surgery, Hiratsuka City Hospital, 1-19-1 Minamihara, Hiratsuka-shi, Kanagawa 254-0065, JapanDepartment of Breast Surgery, Hiratsuka City Hospital, 1-19-1 Minamihara, Hiratsuka-shi, Kanagawa 254-0065, JapanDepartment of Breast Surgery, Hiratsuka City Hospital, 1-19-1 Minamihara, Hiratsuka-shi, Kanagawa 254-0065, JapanPrimary lymphoma of the breast is a rare disease, accounting for about 0.5% of all primary breast tumors. Often found as a solitary indolent mass, it is difficult to distinguish from breast cancer on imaging and is often diagnosed for the first time based on histological findings. Diffuse large B-cell lymphoma is the most common histological subtype. A 48-year-old woman visited our hospital because of a painless mass in the left breast. Breast cancer was suspected based on the imaging findings. A core needle biopsy was performed, and the invasive ductal carcinoma was diagnosed. Partial mastectomy and sentinel lymph node biopsy were performed. The resected specimen was finally diagnosed as diffuse large B-cell lymphoma based on immunohistochemical staining. The patient was treated with R-CHOP and intrathecal injection of methotrexate. The patient remains alive without recurrence 4 years later. Awareness of primary breast lymphoma is essential for accurate and timely diagnosis and avoidance of unnecessary surgery.http://www.sciencedirect.com/science/article/pii/S1930043320305574Primary breast lymphomaBreastImmunohistochemistry |
| spellingShingle | Kimiyasu Yoneyama, MD Motohito Nakagawa, MD,PhD Asuka Hara, MD Primary lymphoma of the breast: A case report and review of the literature Radiology Case Reports Primary breast lymphoma Breast Immunohistochemistry |
| title | Primary lymphoma of the breast: A case report and review of the literature |
| title_full | Primary lymphoma of the breast: A case report and review of the literature |
| title_fullStr | Primary lymphoma of the breast: A case report and review of the literature |
| title_full_unstemmed | Primary lymphoma of the breast: A case report and review of the literature |
| title_short | Primary lymphoma of the breast: A case report and review of the literature |
| title_sort | primary lymphoma of the breast a case report and review of the literature |
| topic | Primary breast lymphoma Breast Immunohistochemistry |
| url | http://www.sciencedirect.com/science/article/pii/S1930043320305574 |
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