Variant Philadelphia translocations with different breakpoints in six chronic myeloid leukemia patients

Variant Philadelphia translocations with different breakpoints in six chronic myeloid leukemia patients

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Objective: The Philadelphia (Ph) chromosome, consisting of the t(9;22)(q34;q11) translocation, is observed in ~90% of patients with chronic myeloid leukemia (CML). Variant Ph translocations are observed in 5%-10% of CML patients. In variant translocations 3 and possibly more chromosomes are involved...

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Bibliographic Details
Main Authors: Dilhan Kuru, Yelda Tarkan Argüden, Muhlis Cem Ar, Ayşe Çırakoğlu, Şeniz Öngören, Şükriye Yılmaz, Ahmet Emre Eşkazan, Ayhan Deviren, Teoman Soysal, Seniha Hacıhanefioğlu, Birsen Ülkü
Format: Article
Language:English
Published: Galenos Publishing House 2011-09-01
Series:Turkish Journal of Hematology
Subjects:
Chronic myeloid leukemia (CML)
variant Ph chromosome
cytogenetics
fluorescence in situ hybridization (FISH)
Online Access:http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-16056

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http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-16056

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