Pigmented squamous cell carcinoma: case report and importance of differential diagnosis
Abstract: A few cases of pigmented squamous cell carcinoma affecting the skin and the ocular and oral mucosa of the elderly have been described in the literature. The disease manifests itself as papular and nodular erythematous or pigmented lesions. The main clinical differential diagnoses are pigme...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2018-02-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000100096&tlng=en |
| _version_ | 1818730958974615552 |
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| author | Patrícia Motta de Morais Antônio Pedro Mendes Schettini Jeanine Alvarenga Rocha Renato Cândido da Silva Júnior |
| author_facet | Patrícia Motta de Morais Antônio Pedro Mendes Schettini Jeanine Alvarenga Rocha Renato Cândido da Silva Júnior |
| author_sort | Patrícia Motta de Morais |
| collection | DOAJ |
| description | Abstract: A few cases of pigmented squamous cell carcinoma affecting the skin and the ocular and oral mucosa of the elderly have been described in the literature. The disease manifests itself as papular and nodular erythematous or pigmented lesions. The main clinical differential diagnoses are pigmented basal cell carcinoma and melanoma. Histopathological examination is characterized by proliferation of atypical squamous cells with formation of horn pearls permeated by dendritic melanocytes. For this reason, a careful diagnosis is necessary to rule out other tumors that show melanin pigment. Surgical removal is the indicated treatment and the prognosis is similar to the classical squamous cell carcinoma. We report a case of pigmented squamous cell carcinoma with diagnosis confirmed by histological and immunohistochemical examinations. |
| first_indexed | 2024-12-17T23:10:04Z |
| format | Article |
| id | doaj.art-2ed26ab3fd8849bd9458418753d76ea1 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-12-17T23:10:04Z |
| publishDate | 2018-02-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-2ed26ab3fd8849bd9458418753d76ea12022-12-21T21:29:10ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962018-02-01931969810.1590/abd1806-4841.20186757Pigmented squamous cell carcinoma: case report and importance of differential diagnosisPatrícia Motta de MoraisAntônio Pedro Mendes SchettiniJeanine Alvarenga RochaRenato Cândido da Silva JúniorAbstract: A few cases of pigmented squamous cell carcinoma affecting the skin and the ocular and oral mucosa of the elderly have been described in the literature. The disease manifests itself as papular and nodular erythematous or pigmented lesions. The main clinical differential diagnoses are pigmented basal cell carcinoma and melanoma. Histopathological examination is characterized by proliferation of atypical squamous cells with formation of horn pearls permeated by dendritic melanocytes. For this reason, a careful diagnosis is necessary to rule out other tumors that show melanin pigment. Surgical removal is the indicated treatment and the prognosis is similar to the classical squamous cell carcinoma. We report a case of pigmented squamous cell carcinoma with diagnosis confirmed by histological and immunohistochemical examinations.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000100096&tlng=enCarcinoma, squamous cellHistologyMelanocytes |
| spellingShingle | Patrícia Motta de Morais Antônio Pedro Mendes Schettini Jeanine Alvarenga Rocha Renato Cândido da Silva Júnior Pigmented squamous cell carcinoma: case report and importance of differential diagnosis Anais Brasileiros de Dermatologia Carcinoma, squamous cell Histology Melanocytes |
| title | Pigmented squamous cell carcinoma: case report and importance of differential diagnosis |
| title_full | Pigmented squamous cell carcinoma: case report and importance of differential diagnosis |
| title_fullStr | Pigmented squamous cell carcinoma: case report and importance of differential diagnosis |
| title_full_unstemmed | Pigmented squamous cell carcinoma: case report and importance of differential diagnosis |
| title_short | Pigmented squamous cell carcinoma: case report and importance of differential diagnosis |
| title_sort | pigmented squamous cell carcinoma case report and importance of differential diagnosis |
| topic | Carcinoma, squamous cell Histology Melanocytes |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000100096&tlng=en |
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