Increased RNA editing in maternal immune activation model of neurodevelopmental disease
Interferon can be induced by the viral mimic PolyI:C, which can in turn activate RNA editing enzymes. Here the authors identify transient changes in A-to-I RNA editing following maternal immune activation in mice.
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-10-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-19048-6 |
| _version_ | 1819022003688964096 |
|---|---|
| author | Hadas Tsivion-Visbord Eli Kopel Ariel Feiglin Tamar Sofer Ran Barzilay Tali Ben-Zur Orly Yaron Daniel Offen Erez Y. Levanon |
| author_facet | Hadas Tsivion-Visbord Eli Kopel Ariel Feiglin Tamar Sofer Ran Barzilay Tali Ben-Zur Orly Yaron Daniel Offen Erez Y. Levanon |
| author_sort | Hadas Tsivion-Visbord |
| collection | DOAJ |
| description | Interferon can be induced by the viral mimic PolyI:C, which can in turn activate RNA editing enzymes. Here the authors identify transient changes in A-to-I RNA editing following maternal immune activation in mice. |
| first_indexed | 2024-12-21T04:16:05Z |
| format | Article |
| id | doaj.art-2ed2b8422be94f928e72f7b89c81639b |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-21T04:16:05Z |
| publishDate | 2020-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-2ed2b8422be94f928e72f7b89c81639b2022-12-21T19:16:19ZengNature PortfolioNature Communications2041-17232020-10-0111111310.1038/s41467-020-19048-6Increased RNA editing in maternal immune activation model of neurodevelopmental diseaseHadas Tsivion-Visbord0Eli Kopel1Ariel Feiglin2Tamar Sofer3Ran Barzilay4Tali Ben-Zur5Orly Yaron6Daniel Offen7Erez Y. Levanon8Sackler Faculty of Medicine, Human Molecular Genetics & Biochemistry, Felsenstein Medical Research Center, Tel-Aviv UniversityThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan UniversityDepartment of Biomedical Informatics, Harvard Medical SchoolDepartments of Medicine and of Biostatistics, Harvard UniversityLifespan Brain Institute Children’s Hospital of Philadelphia and Penn Medicine; the Department of Child and Adolescent Psychiatry and Behavioral Sciences, CHOPSackler Faculty of Medicine, Human Molecular Genetics & Biochemistry, Felsenstein Medical Research Center, Tel-Aviv UniversityThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan UniversitySackler Faculty of Medicine, Human Molecular Genetics & Biochemistry, Felsenstein Medical Research Center, Tel-Aviv UniversityThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan UniversityInterferon can be induced by the viral mimic PolyI:C, which can in turn activate RNA editing enzymes. Here the authors identify transient changes in A-to-I RNA editing following maternal immune activation in mice.https://doi.org/10.1038/s41467-020-19048-6 |
| spellingShingle | Hadas Tsivion-Visbord Eli Kopel Ariel Feiglin Tamar Sofer Ran Barzilay Tali Ben-Zur Orly Yaron Daniel Offen Erez Y. Levanon Increased RNA editing in maternal immune activation model of neurodevelopmental disease Nature Communications |
| title | Increased RNA editing in maternal immune activation model of neurodevelopmental disease |
| title_full | Increased RNA editing in maternal immune activation model of neurodevelopmental disease |
| title_fullStr | Increased RNA editing in maternal immune activation model of neurodevelopmental disease |
| title_full_unstemmed | Increased RNA editing in maternal immune activation model of neurodevelopmental disease |
| title_short | Increased RNA editing in maternal immune activation model of neurodevelopmental disease |
| title_sort | increased rna editing in maternal immune activation model of neurodevelopmental disease |
| url | https://doi.org/10.1038/s41467-020-19048-6 |
| work_keys_str_mv | AT hadastsivionvisbord increasedrnaeditinginmaternalimmuneactivationmodelofneurodevelopmentaldisease AT elikopel increasedrnaeditinginmaternalimmuneactivationmodelofneurodevelopmentaldisease AT arielfeiglin increasedrnaeditinginmaternalimmuneactivationmodelofneurodevelopmentaldisease AT tamarsofer increasedrnaeditinginmaternalimmuneactivationmodelofneurodevelopmentaldisease AT ranbarzilay increasedrnaeditinginmaternalimmuneactivationmodelofneurodevelopmentaldisease AT talibenzur increasedrnaeditinginmaternalimmuneactivationmodelofneurodevelopmentaldisease AT orlyyaron increasedrnaeditinginmaternalimmuneactivationmodelofneurodevelopmentaldisease AT danieloffen increasedrnaeditinginmaternalimmuneactivationmodelofneurodevelopmentaldisease AT erezylevanon increasedrnaeditinginmaternalimmuneactivationmodelofneurodevelopmentaldisease |