Selective cerebral perfusion with 4-branch graft total aortic arch replacement: Outcomes in 12 patients

<p>Abstract</p> <p>Background</p> <p>Aortic arch reconstruction is associated with high neurological morbidity. Our purpose is to describe our experience using a 4-branched graft and selective antegrade brain perfusion (SABP) for total aortic arch replacement (TAR).<...

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Bibliographic Details
Main Authors: Lai Wei-Liang, Hsu Chiao-Po, Shih Chung-Che, Li Ming-Li, Li Ping-chun
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Online Access:http://www.cardiothoracicsurgery.org/content/7/1/32
Description
Summary:<p>Abstract</p> <p>Background</p> <p>Aortic arch reconstruction is associated with high neurological morbidity. Our purpose is to describe our experience using a 4-branched graft and selective antegrade brain perfusion (SABP) for total aortic arch replacement (TAR).</p> <p>Methods</p> <p>We retrospectively reviewed the medical records of 12 patients who received TAR, with or without ascending aorta replacement, with a 4-branched graft for Stanford type A dissection (<it>n </it>= 9) or aortic arch aneurysm (<it>n </it>= 3). In all patients surgery was performed with deep hypothermic circulatory arrest (DHCA) with or without retrograde brain perfusion, and selective antegrade brain perfusion (SABP) via the subclavian artery or axillary artery.</p> <p>Results</p> <p>There were 8 males and 4 females with an average age of 63.14 years. Emergent operations were performed in 9 patients with acute type A aortic dissections. Of all 12 patients, 2 deaths occurred and 1 patient experienced lower extremity paraplegia resulting in an in-hospital mortality rate of 16.6% and a permanent neurological deficit rate of 8.3%.</p> <p>Conclusions</p> <p>The use of a 4-branched graft, hypothermic circulatory arrest, and SABP is a useful operative method for aortic arch replacement with acceptable morbidity and mortality.</p>
ISSN:1749-8090