Selective cerebral perfusion with 4-branch graft total aortic arch replacement: Outcomes in 12 patients

<p>Abstract</p> <p>Background</p> <p>Aortic arch reconstruction is associated with high neurological morbidity. Our purpose is to describe our experience using a 4-branched graft and selective antegrade brain perfusion (SABP) for total aortic arch replacement (TAR).<...

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Main Authors: Lai Wei-Liang, Hsu Chiao-Po, Shih Chung-Che, Li Ming-Li, Li Ping-chun
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Online Access:http://www.cardiothoracicsurgery.org/content/7/1/32
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author Lai Wei-Liang
Hsu Chiao-Po
Shih Chung-Che
Li Ming-Li
Li Ping-chun
author_facet Lai Wei-Liang
Hsu Chiao-Po
Shih Chung-Che
Li Ming-Li
Li Ping-chun
author_sort Lai Wei-Liang
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Aortic arch reconstruction is associated with high neurological morbidity. Our purpose is to describe our experience using a 4-branched graft and selective antegrade brain perfusion (SABP) for total aortic arch replacement (TAR).</p> <p>Methods</p> <p>We retrospectively reviewed the medical records of 12 patients who received TAR, with or without ascending aorta replacement, with a 4-branched graft for Stanford type A dissection (<it>n </it>= 9) or aortic arch aneurysm (<it>n </it>= 3). In all patients surgery was performed with deep hypothermic circulatory arrest (DHCA) with or without retrograde brain perfusion, and selective antegrade brain perfusion (SABP) via the subclavian artery or axillary artery.</p> <p>Results</p> <p>There were 8 males and 4 females with an average age of 63.14 years. Emergent operations were performed in 9 patients with acute type A aortic dissections. Of all 12 patients, 2 deaths occurred and 1 patient experienced lower extremity paraplegia resulting in an in-hospital mortality rate of 16.6% and a permanent neurological deficit rate of 8.3%.</p> <p>Conclusions</p> <p>The use of a 4-branched graft, hypothermic circulatory arrest, and SABP is a useful operative method for aortic arch replacement with acceptable morbidity and mortality.</p>
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spelling doaj.art-2ed3d9fc7e5c427b8a7ec730e4ca1ab42022-12-22T01:07:11ZengBMCJournal of Cardiothoracic Surgery1749-80902012-04-01713210.1186/1749-8090-7-32Selective cerebral perfusion with 4-branch graft total aortic arch replacement: Outcomes in 12 patientsLai Wei-LiangHsu Chiao-PoShih Chung-CheLi Ming-LiLi Ping-chun<p>Abstract</p> <p>Background</p> <p>Aortic arch reconstruction is associated with high neurological morbidity. Our purpose is to describe our experience using a 4-branched graft and selective antegrade brain perfusion (SABP) for total aortic arch replacement (TAR).</p> <p>Methods</p> <p>We retrospectively reviewed the medical records of 12 patients who received TAR, with or without ascending aorta replacement, with a 4-branched graft for Stanford type A dissection (<it>n </it>= 9) or aortic arch aneurysm (<it>n </it>= 3). In all patients surgery was performed with deep hypothermic circulatory arrest (DHCA) with or without retrograde brain perfusion, and selective antegrade brain perfusion (SABP) via the subclavian artery or axillary artery.</p> <p>Results</p> <p>There were 8 males and 4 females with an average age of 63.14 years. Emergent operations were performed in 9 patients with acute type A aortic dissections. Of all 12 patients, 2 deaths occurred and 1 patient experienced lower extremity paraplegia resulting in an in-hospital mortality rate of 16.6% and a permanent neurological deficit rate of 8.3%.</p> <p>Conclusions</p> <p>The use of a 4-branched graft, hypothermic circulatory arrest, and SABP is a useful operative method for aortic arch replacement with acceptable morbidity and mortality.</p>http://www.cardiothoracicsurgery.org/content/7/1/32Aortic arch aneurysmType A aortic dissectionBranched aortic graft
spellingShingle Lai Wei-Liang
Hsu Chiao-Po
Shih Chung-Che
Li Ming-Li
Li Ping-chun
Selective cerebral perfusion with 4-branch graft total aortic arch replacement: Outcomes in 12 patients
Journal of Cardiothoracic Surgery
Aortic arch aneurysm
Type A aortic dissection
Branched aortic graft
title Selective cerebral perfusion with 4-branch graft total aortic arch replacement: Outcomes in 12 patients
title_full Selective cerebral perfusion with 4-branch graft total aortic arch replacement: Outcomes in 12 patients
title_fullStr Selective cerebral perfusion with 4-branch graft total aortic arch replacement: Outcomes in 12 patients
title_full_unstemmed Selective cerebral perfusion with 4-branch graft total aortic arch replacement: Outcomes in 12 patients
title_short Selective cerebral perfusion with 4-branch graft total aortic arch replacement: Outcomes in 12 patients
title_sort selective cerebral perfusion with 4 branch graft total aortic arch replacement outcomes in 12 patients
topic Aortic arch aneurysm
Type A aortic dissection
Branched aortic graft
url http://www.cardiothoracicsurgery.org/content/7/1/32
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AT shihchungche selectivecerebralperfusionwith4branchgrafttotalaorticarchreplacementoutcomesin12patients
AT limingli selectivecerebralperfusionwith4branchgrafttotalaorticarchreplacementoutcomesin12patients
AT lipingchun selectivecerebralperfusionwith4branchgrafttotalaorticarchreplacementoutcomesin12patients