Syphilitic infection and pathological pregnancy, childbirth and the changes of the placenta

It is now known that one of the main causes of pathology of pregnancy, childbirth and placenta, is infection. The purpose of the study. To reveal the peculiarities of pregnancy and delivery, as well as histological changes of placenta in syphilitic infection, depending on the time of detection of th...

Full description

Bibliographic Details
Main Authors: N. V. Matyskina, T. E. Taranushenko, V. I. Prokhorenkov
Format: Article
Language:English
Published: State Scientific Center of Dermatovenereology and Cosmetology 2017-08-01
Series:Vestnik Dermatologii i Venerologii
Subjects:
Online Access:https://www.vestnikdv.ru/jour/article/view/163
_version_ 1797722890426122240
author N. V. Matyskina
T. E. Taranushenko
V. I. Prokhorenkov
author_facet N. V. Matyskina
T. E. Taranushenko
V. I. Prokhorenkov
author_sort N. V. Matyskina
collection DOAJ
description It is now known that one of the main causes of pathology of pregnancy, childbirth and placenta, is infection. The purpose of the study. To reveal the peculiarities of pregnancy and delivery, as well as histological changes of placenta in syphilitic infection, depending on the time of detection of the disease. The materials and methods of research. Under the supervision of 114 women with confirmed syphilis infection. In accordance with the intended purpose of the study three groups of women with syphilitic infection. Group I included 42 women who are diagnosed with syphilis installed for the first time in this period of pregnancy or nursing home. II group consisted of 34 women who have had syphilis prior to the present pregnancy had been trained in specific therapies, but during this pregnancy had a positive DAC. In the third group consisted of 38 women who had syphilis and received a course of specific therapy prior to the present pregnancy, with a negative DAC during this pregnancy. The control group included 30 women without a history of syphilis. Results and discussion. We found a significant increase in the overall frequency of complications in childbirth in women with syphilitic infection, the most common manifestation of the pathology of childbirth should be considered the changing nature of amniotic fluid and the need for manual examination of the uterine cavity. Degenerative changes in the form of petrification was absent in the control group and identified in women I-III bands 21.4-28.9 percent. Inflammatory changes of the placenta was detected with significantly higher frequency in group I. We found a significant prevalence of pathological changes in the stroma of the villi in placentas in groups I-III compared with the control. Conclusion. Leading macro- and microscopic pathological disorders of the placenta, concomitant syphilitic infection and emerging at 16-18 weeks of gestation and may be involved in the development of complications of pregnancy and childbirth.
first_indexed 2024-03-12T09:54:18Z
format Article
id doaj.art-2ed7f7acc0a34715a0508698958933b0
institution Directory Open Access Journal
issn 0042-4609
2313-6294
language English
last_indexed 2024-03-12T09:54:18Z
publishDate 2017-08-01
publisher State Scientific Center of Dermatovenereology and Cosmetology
record_format Article
series Vestnik Dermatologii i Venerologii
spelling doaj.art-2ed7f7acc0a34715a0508698958933b02023-09-02T12:17:07ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942017-08-0104697510.25208/0042-4609-2015-0-4-69-75162Syphilitic infection and pathological pregnancy, childbirth and the changes of the placentaN. V. Matyskina0T. E. Taranushenko1V. I. Prokhorenkov2Krasnoyarsk State Medical UniversityKrasnoyarsk State Medical UniversityKrasnoyarsk State Medical UniversityIt is now known that one of the main causes of pathology of pregnancy, childbirth and placenta, is infection. The purpose of the study. To reveal the peculiarities of pregnancy and delivery, as well as histological changes of placenta in syphilitic infection, depending on the time of detection of the disease. The materials and methods of research. Under the supervision of 114 women with confirmed syphilis infection. In accordance with the intended purpose of the study three groups of women with syphilitic infection. Group I included 42 women who are diagnosed with syphilis installed for the first time in this period of pregnancy or nursing home. II group consisted of 34 women who have had syphilis prior to the present pregnancy had been trained in specific therapies, but during this pregnancy had a positive DAC. In the third group consisted of 38 women who had syphilis and received a course of specific therapy prior to the present pregnancy, with a negative DAC during this pregnancy. The control group included 30 women without a history of syphilis. Results and discussion. We found a significant increase in the overall frequency of complications in childbirth in women with syphilitic infection, the most common manifestation of the pathology of childbirth should be considered the changing nature of amniotic fluid and the need for manual examination of the uterine cavity. Degenerative changes in the form of petrification was absent in the control group and identified in women I-III bands 21.4-28.9 percent. Inflammatory changes of the placenta was detected with significantly higher frequency in group I. We found a significant prevalence of pathological changes in the stroma of the villi in placentas in groups I-III compared with the control. Conclusion. Leading macro- and microscopic pathological disorders of the placenta, concomitant syphilitic infection and emerging at 16-18 weeks of gestation and may be involved in the development of complications of pregnancy and childbirth.https://www.vestnikdv.ru/jour/article/view/163сифилисбеременная женщинаплацентапатоморфологические измененияsyphilispregnant womanplacentapathomorphological changes
spellingShingle N. V. Matyskina
T. E. Taranushenko
V. I. Prokhorenkov
Syphilitic infection and pathological pregnancy, childbirth and the changes of the placenta
Vestnik Dermatologii i Venerologii
сифилис
беременная женщина
плацента
патоморфологические изменения
syphilis
pregnant woman
placenta
pathomorphological changes
title Syphilitic infection and pathological pregnancy, childbirth and the changes of the placenta
title_full Syphilitic infection and pathological pregnancy, childbirth and the changes of the placenta
title_fullStr Syphilitic infection and pathological pregnancy, childbirth and the changes of the placenta
title_full_unstemmed Syphilitic infection and pathological pregnancy, childbirth and the changes of the placenta
title_short Syphilitic infection and pathological pregnancy, childbirth and the changes of the placenta
title_sort syphilitic infection and pathological pregnancy childbirth and the changes of the placenta
topic сифилис
беременная женщина
плацента
патоморфологические изменения
syphilis
pregnant woman
placenta
pathomorphological changes
url https://www.vestnikdv.ru/jour/article/view/163
work_keys_str_mv AT nvmatyskina syphiliticinfectionandpathologicalpregnancychildbirthandthechangesoftheplacenta
AT tetaranushenko syphiliticinfectionandpathologicalpregnancychildbirthandthechangesoftheplacenta
AT viprokhorenkov syphiliticinfectionandpathologicalpregnancychildbirthandthechangesoftheplacenta