Phytol Suppresses Osteoclast Differentiation and Oxidative Stress through Nrf2/HO-1 Regulation in RANKL-Induced RAW264.7 Cells

Phytol Suppresses Osteoclast Differentiation and Oxidative Stress through Nrf2/HO-1 Regulation in RANKL-Induced RAW264.7 Cells

Osteoporosis is a systemic skeletal disorder where osteoclasts are prevalent among osteoblasts. Oxidative stress is one of the main causes of osteoporosis, and nuclear factor erythroid-2-related factor 2 (Nrf2) is the master regulator of antioxidant responses. Phytol, a diterpene isolated from <i...

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Bibliographic Details
Main Authors:	Eun-Nam Kim, Nguyen Minh Trang, Heesun Kang, Ki Hyun Kim, Gil-Saeng Jeong
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Series:	Cells
Subjects:	phytol Nrf2 oxidative stress siRNA osteoclast
Online Access:	https://www.mdpi.com/2073-4409/11/22/3596

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