Species-Specific Plant-Derived Nanoparticle Characteristics
Medicinal and agricultural plants contain numerous phytochemical compounds with pronounced biological effects on human health. They are known to encapsulate most of their characteristic bioactive compounds within membranous elements of intercellular communication known as exosomes. These nanovesicle...
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| Natura: | Articolo |
| Lingua: | English |
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MDPI AG
2022-11-01
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| Serie: | Plants |
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| Accesso online: | https://www.mdpi.com/2223-7747/11/22/3139 |
| _version_ | 1827643840416186368 |
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| author | Akvilė Viršilė Giedrė Samuolienė Kristina Laužikė Emilija Šipailaitė Zbigniev Balion Aistė Jekabsone |
| author_facet | Akvilė Viršilė Giedrė Samuolienė Kristina Laužikė Emilija Šipailaitė Zbigniev Balion Aistė Jekabsone |
| author_sort | Akvilė Viršilė |
| collection | DOAJ |
| description | Medicinal and agricultural plants contain numerous phytochemical compounds with pronounced biological effects on human health. They are known to encapsulate most of their characteristic bioactive compounds within membranous elements of intercellular communication known as exosomes. These nanovesicles serve as capsules protecting their biological activity and improving their penetration into the tissue. Therefore, the application of plant exosome preparations holds considerable potential for cosmetics and pharmacy, but the quality and consistency of plant material for exosome isolation is of critical importance. Therefore, in this study, we aimed to evaluate yield, size distribution patterns, and antioxidant properties between nanovesicle preparations of the following portfolio of medicinal plants: <i>Kalanchoe daigremontiana</i>, <i>Artemisia absinthium</i>, <i>Hypericum perforatum</i>, <i>Silybum marianum</i>, <i>Chelidonium</i> majus, and <i>Scutellaria baicalensis</i>. Results showed that nanoparticle yield, size distribution, and antioxidant activities were specific to plant species. Compared to other plants, nanoparticle preparations from <i>Artemisia absinthium</i> were distinguished by remarkably higher yield and concentration, while the highest antioxidant activity of plant-derived nanoparticle preparations per weight and per particle was determined to occur in <i>Chelidonium majus</i> and <i>Hypericum perforatum</i> samples. Results showed no significant correlation in DPPH (2-diphenyl-1-picrylhydrazyl) free radical scavenging activity and FRAP (ferric reducing antioxidant power) between plant material and nanoparticle preparations. More detailed biochemical analysis of exosome preparations is necessary to validate their biological activity and its relation to source plant cells. |
| first_indexed | 2024-03-09T18:03:46Z |
| format | Article |
| id | doaj.art-2edf155ac4c04b51a90577ae3c6435be |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-09T18:03:46Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-2edf155ac4c04b51a90577ae3c6435be2023-11-24T09:40:15ZengMDPI AGPlants2223-77472022-11-011122313910.3390/plants11223139Species-Specific Plant-Derived Nanoparticle CharacteristicsAkvilė Viršilė0Giedrė Samuolienė1Kristina Laužikė2Emilija Šipailaitė3Zbigniev Balion4Aistė Jekabsone5Lithuanian Research Centre for Agriculture and Forestry, Institute of Horticulture, Kauno Str. 30, 54333 Babtai, LithuaniaLithuanian Research Centre for Agriculture and Forestry, Institute of Horticulture, Kauno Str. 30, 54333 Babtai, LithuaniaLithuanian Research Centre for Agriculture and Forestry, Institute of Horticulture, Kauno Str. 30, 54333 Babtai, LithuaniaInstitute of Pharmaceutical Technologies, Faculty of Pharmacy, Lithuanian University of Health Sciences, 50161 Kaunas, LithuaniaInstitute of Pharmaceutical Technologies, Faculty of Pharmacy, Lithuanian University of Health Sciences, 50161 Kaunas, LithuaniaInstitute of Pharmaceutical Technologies, Faculty of Pharmacy, Lithuanian University of Health Sciences, 50161 Kaunas, LithuaniaMedicinal and agricultural plants contain numerous phytochemical compounds with pronounced biological effects on human health. They are known to encapsulate most of their characteristic bioactive compounds within membranous elements of intercellular communication known as exosomes. These nanovesicles serve as capsules protecting their biological activity and improving their penetration into the tissue. Therefore, the application of plant exosome preparations holds considerable potential for cosmetics and pharmacy, but the quality and consistency of plant material for exosome isolation is of critical importance. Therefore, in this study, we aimed to evaluate yield, size distribution patterns, and antioxidant properties between nanovesicle preparations of the following portfolio of medicinal plants: <i>Kalanchoe daigremontiana</i>, <i>Artemisia absinthium</i>, <i>Hypericum perforatum</i>, <i>Silybum marianum</i>, <i>Chelidonium</i> majus, and <i>Scutellaria baicalensis</i>. Results showed that nanoparticle yield, size distribution, and antioxidant activities were specific to plant species. Compared to other plants, nanoparticle preparations from <i>Artemisia absinthium</i> were distinguished by remarkably higher yield and concentration, while the highest antioxidant activity of plant-derived nanoparticle preparations per weight and per particle was determined to occur in <i>Chelidonium majus</i> and <i>Hypericum perforatum</i> samples. Results showed no significant correlation in DPPH (2-diphenyl-1-picrylhydrazyl) free radical scavenging activity and FRAP (ferric reducing antioxidant power) between plant material and nanoparticle preparations. More detailed biochemical analysis of exosome preparations is necessary to validate their biological activity and its relation to source plant cells.https://www.mdpi.com/2223-7747/11/22/3139antioxidant activityplant-derived nanovesiclesmedicinal plantsplant speciessize distribution |
| spellingShingle | Akvilė Viršilė Giedrė Samuolienė Kristina Laužikė Emilija Šipailaitė Zbigniev Balion Aistė Jekabsone Species-Specific Plant-Derived Nanoparticle Characteristics Plants antioxidant activity plant-derived nanovesicles medicinal plants plant species size distribution |
| title | Species-Specific Plant-Derived Nanoparticle Characteristics |
| title_full | Species-Specific Plant-Derived Nanoparticle Characteristics |
| title_fullStr | Species-Specific Plant-Derived Nanoparticle Characteristics |
| title_full_unstemmed | Species-Specific Plant-Derived Nanoparticle Characteristics |
| title_short | Species-Specific Plant-Derived Nanoparticle Characteristics |
| title_sort | species specific plant derived nanoparticle characteristics |
| topic | antioxidant activity plant-derived nanovesicles medicinal plants plant species size distribution |
| url | https://www.mdpi.com/2223-7747/11/22/3139 |
| work_keys_str_mv | AT akvilevirsile speciesspecificplantderivednanoparticlecharacteristics AT giedresamuoliene speciesspecificplantderivednanoparticlecharacteristics AT kristinalauzike speciesspecificplantderivednanoparticlecharacteristics AT emilijasipailaite speciesspecificplantderivednanoparticlecharacteristics AT zbignievbalion speciesspecificplantderivednanoparticlecharacteristics AT aistejekabsone speciesspecificplantderivednanoparticlecharacteristics |