A global in vivo Drosophila RNAi screen identifies a key role of ceramide phosphoethanolamine for glial ensheathment of axons.

Glia are of vital importance for all complex nervous system. One of the many functions of glia is to insulate and provide trophic and metabolic support to axons. Here, using glial-specific RNAi knockdown in Drosophila, we silenced 6930 conserved genes in adult flies to identify essential genes and p...

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Váldodahkkit: Aniket Ghosh, Tina Kling, Nicolas Snaidero, Julio L Sampaio, Andrej Shevchenko, Heribert Gras, Bart Geurten, Martin C Göpfert, Jörg B Schulz, Aaron Voigt, Mikael Simons
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Public Library of Science (PLoS) 2013-01-01
Ráidu:PLoS Genetics
Liŋkkat:http://europepmc.org/articles/PMC3861124?pdf=render